Evidence map›Paper›PMID 42879584›Full record

Trial reportRevista da Associacao Medica Brasileira (1992)2026

Osteopathic manual therapy in fibromyalgia: a pilot study.

Aziz Dengiz, Elif Gur Kabul, Gulsum Tikac, Bilge Basakci Calik, Uğur Karasu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aziz DengizGaziantep Islam Science and Technology University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Gaziantep, Türkiye.ORCID http://orcid.org/0000-0003-3492-7448
Elif Gur KabulUsak University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Uşak, Türkiye.ORCID http://orcid.org/0000-0003-3209-1499
Gulsum TikacSiirt University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation - Siirt, Türkiye.ORCID http://orcid.org/0000-0001-7375-6747
Bilge Basakci CalikPamukkale University, Faculty of Physiotherapy and Rehabilitation, Department of Orthopedic Rehabilitation - Denizli, Türkiye.ORCID http://orcid.org/0000-0002-7267-7622
Uğur KarasuPamukkale University, Faculty of Medicine, Department of Internal Medicine - Denizli, Türkiye.ORCID http://orcid.org/0000-0003-0090-0247

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this pilot study was to evaluate the preliminary efficacy and feasibility of integrating Osteopathic Manual Therapy Techniques combined with Clinical Pilates on pain, symptom severity, and sleep quality in patients with fibromyalgia.

methodsTwenty women with fibromyalgia were randomized into Osteopathic Manual Therapy Techniques+Clinical Pilates (n=11) and Clinical Pilates (n=9) groups. The protocol lasted 6 weeks (3 sessions/week). Osteopathic Manual Therapy Techniques included rib raising, suboccipital myofascial release, Sternocleidomastoid (SCM) mobilization, diaphragm/mediastinum techniques, and visceral mobilizations. Primary outcomes were the Widespread Pain Index, Symptom Severity Scale, and Pressure Pain Threshold. Sleep was assessed via the Pittsburgh Sleep Quality Index.

resultsBoth groups showed significant intra-group improvements (p<0.05). Within-group analyses revealed that the Osteopathic Manual Therapy Techniques+Clinical Pilates group achieved significant improvements in Widespread Pain Index (p=0.003), Symptom Severity Scale (p=0.005), and Pittsburgh Sleep Quality Index (p=0.007). However, in the between-group analysis of change scores, the Osteopathic Manual Therapy Techniques+Clinical Pilates group demonstrated significantly superior improvements exclusively in sleep quality (Pittsburgh Sleep Quality Index, p=0.034) and maximal Pressure Pain Threshold at the trapezius (p=0.035) compared to the Clinical Pilates-only group, while between-group differences for Widespread Pain Index and Symptom Severity Scale did not reach statistical significance (p>0.05).

conclusionIntegrating Osteopathic Manual Therapy Techniques into exercise-based rehabilitation presents promising preliminary evidence for enhancing central sensitization symptoms and sleep quality in fibromyalgia patients, though larger trials are needed.

Indexed as

Exercise Movement TechniquesFibromyalgiaManipulation, OsteopathicAdultFeasibility StudiesFemaleHumansMiddle AgedPain MeasurementPain ThresholdPilot ProjectsSeverity of Illness IndexSleep QualityTreatment Outcome

Identifiers

PMID42879584
PMCPMC13661034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.