Evidence map›Paper›PMID 42879427›Full record

ArticlePLoS computational biology2026

Ten simple rules to build genomics capacity for routine laboratory practice in the Global South.

Emilyn Costa Conceição, Abhinav Sharma, Davi Josué Marcon, Layana Rufino Ribeiro, Danna Karen Corrêa Dos Santos, Lilian Eduarda de Oliveira Freitas, Alex Brito Souza, Hendor Neves Ribeiro de Jesus, Maria Cristina da Silva Lourenço, Valnete das Graças Dantas Andrade and 13 more

Abstract read
In one paragraph

Article in PLoS computational biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Emilyn Costa ConceiçãoSouth African Medical Research Council Centre for Tuberculosis Research (SAMRC), Division of Molecular Biology and Human Genetics (MBHG), Biomedical Research Institute (BMRI), Faculty of Medicine and Health Sciences (FMHS), Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-7445-6620
Abhinav SharmaSouth African Medical Research Council Centre for Tuberculosis Research (SAMRC), Division of Molecular Biology and Human Genetics (MBHG), Biomedical Research Institute (BMRI), Faculty of Medicine and Health Sciences (FMHS), Stellenbosch University, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-6402-6993
Davi Josué MarconPrograma de Pós-graduação em Biologia Parasitária na Amazônia (PPG-BPA), Universidade do Estado do Pará (UEPA), Belém, Pará, Brazil.
Layana Rufino RibeiroSeção de Bacteriologia e Micologia (SABMI), Instituto Evandro Chagas (IEC), Ananindeua, Pará, Brazil.
Danna Karen Corrêa Dos SantosPrograma de Pós-graduação em Biologia Parasitária na Amazônia (PPG-BPA), Universidade do Estado do Pará (UEPA), Belém, Pará, Brazil.ORCID https://orcid.org/0000-0003-0221-2755
Lilian Eduarda de Oliveira FreitasLaboratório Central do Amazonas (LACEN-AM), Fundação de Vigilância em Saúde do Amazonas Dra. Rosemary Costa Pinto (FVS-RCP), Manaus, Amazonas, Brazil.
Alex Brito SouzaPrograma de Pós-graduação em Biologia Parasitária na Amazônia (PPG-BPA), Universidade do Estado do Pará (UEPA), Belém, Pará, Brazil.
Hendor Neves Ribeiro de JesusInstituto Gonçalo Moniz (IMG), Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Bahia, Brazil.
Maria Cristina da Silva LourençoLaboratório de Bacteriologia e Bioensaios em Micobactérias, Instituto Nacional de Infectologia Evandro Chagas (INI), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil.
Valnete das Graças Dantas AndradeLaboratório Central do Pará (LACEN-PA), Belém, Pará, Brazil.
Marco Aurélio Almeida de OliveiraLaboratório Central do Amazonas (LACEN-AM), Fundação de Vigilância em Saúde do Amazonas Dra. Rosemary Costa Pinto (FVS-RCP), Manaus, Amazonas, Brazil.
Tatyana Costa Amorim RamosLaboratório Central do Amazonas (LACEN-AM), Fundação de Vigilância em Saúde do Amazonas Dra. Rosemary Costa Pinto (FVS-RCP), Manaus, Amazonas, Brazil.
Ítalo José Mesquita CavalcanteLaboratório Central do Ceará (LACEN-CE), Fortaleza, Ceará, Brazil.
Arabela Leal E Silva de MeloLaboratório Central da Bahia (LACEN-BA), Salvador, Bahia, Brazil.
Nabila IsmailSouth African Medical Research Council Centre for Tuberculosis Research (SAMRC), Division of Molecular Biology and Human Genetics (MBHG), Biomedical Research Institute (BMRI), Faculty of Medicine and Health Sciences (FMHS), Stellenbosch University, Cape Town, South Africa.
Tulio de OliveiraCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Robin Mark WarrenSouth African Medical Research Council Centre for Tuberculosis Research (SAMRC), Division of Molecular Biology and Human Genetics (MBHG), Biomedical Research Institute (BMRI), Faculty of Medicine and Health Sciences (FMHS), Stellenbosch University, Cape Town, South Africa.
Adriana Ayden FerreiraLaboratório Central do Amazonas (LACEN-AM), Fundação de Vigilância em Saúde do Amazonas Dra. Rosemary Costa Pinto (FVS-RCP), Manaus, Amazonas, Brazil.
Theolis Costa Barbosa BessaRede Brasileira de Pesquisas em Tuberculose (REDE-TB), Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-1928-0404
Cristiane Cunha FrotaPrograma de Pós-graduação em Patologia, Universidade Federal do Ceará (UFC), Fortaleza, Ceará, Brazil.ORCID https://orcid.org/0000-0003-0018-7736
Philip Noel SuffysLaboratório de Biologia Molecular Aplicada a Micobacterias, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0001-8527-9300
Karla Valéria Batista LimaPrograma de Pós-graduação em Biologia Parasitária na Amazônia (PPG-BPA), Universidade do Estado do Pará (UEPA), Belém, Pará, Brazil.
REVIGET Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing sustainable genomics capacity in the Global South requires more than technology transfer; it depends on human-centered approaches based on the workflows and existing expertise of laboratory personnel, institutional collaboration, and long-term integration into health systems. Drawing on lessons learned from regional capacity-building initiatives, this article proposes ten simple rules for implementing and sustaining genomics capacity within public health and clinical laboratory settings. These rules emphasize local context, strategic planning, continuous learning, and equitable collaboration. Together, they provide a roadmap for laboratories aiming to transform genomic technologies from research tools for diagnosis, surveillance and decision-making, into routine instruments for public health in low- and middle-income countries.

Indexed as

Capacity BuildingGenomicsLaboratoriesHumansPublic Health

Identifiers

PMID42879427
PMCPMC13671508

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.