ArticleAnnals of biomedical engineering2026
Automated 3D Analysis of Hip Morphology in a Young Adult Population.
Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeAlthough many factors contribute to the development of hip OA, structural findings, such as acetabular dysplasia, are recognized as strong contributing factors to early degenerative changes. However, conventional two-dimensional imaging cannot fully capture the joint's three-dimensional anatomy. This study aimed to develop and validate an automated MRI-based method for 3D hip morphology analysis.
methodsMRI data from 2,454 participants in the Generation R Cohort (1,199 males; 1,255 females; mean age 18.4 years; mean BMI 22.7 kg/m
resultsThe model achieved Dice scores of 0.97 for femoral bone, 0.90 for acetabular bone, 0.76 for femoral cartilage, and 0.77 for acetabular cartilage. Reference ranges were established for all biomarkers. Significant differences were observed between males and females and across BMI groups.
conclusionAutomated 3D hip morphology analysis using MRI is feasible and reliable. The generated reference values enhance understanding of hip development and anatomical variation in young adults and support future large-scale, reproducible assessments. All developed code is made openly available at https://gitlab.com/radiology/msk/genr/hip/hip-segmentation-and-biomarkers.
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