Evidence map›Paper›PMID 42879059›Full record

ArticleStress biology2026

Distinct cadmium detoxicity response between rice cultivars carrying functional or loss-of-function OsHMA3 allele.

Fuqing Sui, Jing Tian, Ziyuan Yang, Yanzheng Yang, Chang Li, Hongen Liu, Jiali Yan, Peng Zhao

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Article in Stress biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Fuqing SuiKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Jing TianKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Ziyuan YangKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Yanzheng YangKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Chang LiKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Hongen LiuKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China.
Jiali YanCollege of Civil and Architecture Engineering, Chuzhou University, Chuzhou, 239000, China. jialiyan092@163.com.
Peng ZhaoKey Laboratory of Soil Pollution Control and Remediation of Henan Province, College of Resources and Environment, Henan Agricultural University, Zhengzhou, China. zhaopeng@henau.edu.cn.

Funding

Key Technology Research and Development Program of Henan Province 232102320117the National Key Research and Development Program of China 2021YFD1700900the National Natural Science Foundation of China 42107049
6 · The paper itself

Abstract

BACKGROUND AND

aimsPlants encounter various abiotic stress during their growth, making it essential to understand their responses to such challenges. Though function of OsHMA3 in cadmium (Cd) sequestration into rice root vacuoles has been well characterized, little is known about how different OsHMA3 alleles influence plant responses to high Cd exposure.

methodsIn this study, we utilized rice cultivars carrying a functional OsHMA3 allele (9311) and a loss-of-function OsHMA3 allele (W4) to investigate their differences in Cd detoxification responses. Morphological, physiological and subcellular changes, as well as Cd species were analyzed.

resultsThe results indicated that Cd was more extensively transported to shoots in W4 than 9311 as expected. However, W4 exhibited a more pronounced growth inhibition with reductions in shoot and root length, more severe leaf chlorosis with chlorophyll a, b, and carotenoid levels decreased by 31%, 43%, and 45% in W4, respectively, while no significant reductions were observed in 9311. Enhanced cell ultrastructural damage, including membranolytic changes, nuclear membrane lysis, and damage to the nucleus, was noted in W4, while, relatively normal cell structure in 9311. The antioxidant enzyme systems exhibited greater responses in W4 than those in 9311. Additionally, lower levels of nitrate/nitrite, chloride, and aminophenol Cd forms were found in W4 roots, while higher concentrations of these were observed in shoots, indicating distinct Cd detoxicity response between W4 and 9311.

conclusionThis study underscores the significance of the OsHMA3 gene in Cd detoxification responses, offering valuable insights into the mechanisms of plant Cd detoxification.

Indexed as

CadmiumDetoxicityOsHMA3Rice varietiesTolerance mechanism

Identifiers

PMID42879059

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