Evidence map›Paper›PMID 42878969›Full record

ArticleIntensive care medicine experimental2026

Esophageal resonance Raman spectroscopy tracks mixed venous oxygenation in experimental shock and hypoxemia.

Tysen DeWaard, Bonne L Keijer, Franklin Ducatez, Cassidy Ferron, Jason Zhang, Yifeng Peng, Padraic Romfh, John N Kheir

Abstract read
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In one paragraph

Article in Intensive care medicine experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tysen DeWaard *Department of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA.
Bonne L Keijer *Department of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA.
Franklin DucatezDepartment of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA.
Cassidy FerronDepartment of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA.
Jason ZhangPendar Medical, LLC, Cambridge, 02138, MA, USA.
Yifeng PengDepartment of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA.
Padraic RomfhPendar Medical, LLC, Cambridge, 02138, MA, USA.
John N KheirDepartment of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital, 300 Longwood Avenue, Boston, 02115, MA, USA. john.kheir@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-6080-8739

Funding

Office of the AssistantSecretary of Defense for Health Affairs W81XWH-19-1-0472.
6 · The paper itself

Abstract

introductionMixed venous oxygen saturation (SvO

methodsA miniaturized 405 nm resonance Raman spectroscopy (RRS) probe was developed to quantify esophageal regional capillary hemoglobin saturation (S

resultsIn both models, baseline S

conclusionsEsophageal RRS enables molecularly specific measurement of regional capillary hemoglobin oxygen saturation and thereby tracks SvO

Indexed as

Hemorrhagic shockHypoxiaMixed venous oxygen saturationResonance Raman spectroscopy

Identifiers

PMID42878969

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.