Evidence map›Paper›PMID 42878947›Full record

ReviewCurrent cardiology reports2026

Infection Prevention and Device Pocket Management in Cardiac Implantable Electronic Devices: Emerging Strategies.

Benito Jonas Baldauf, Kerstin Bode, Ojan Assadian, Marzia Giaccardi, Pasquale Notarstefano, Ahmet Adiyaman, Martin Hemels, Ernest W Lau, Hendrik Bonnemeier

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benito Jonas BaldaufLife Sciences, University of Applied Sciences Bremerhaven, An der Karlstadt 8, Bremerhaven, 27568, Germany. benito.baldauf@hs-bremerhaven.de.
Kerstin BodeDepartment of Electrophysiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Ojan AssadianInstitute for Skin Integrity, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
Marzia GiaccardiDepartment of Cardiology, Santa Maria Annunziata Hospital, Florence, Italy.
Pasquale NotarstefanoDepartment of Cardiology, San Donato Hospital, Arezzo, Italy.
Ahmet AdiyamanDepartment of Cardiology, Isala Hospital, Zwolle, The Netherlands.
Martin HemelsDepartment of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.
Ernest W LauDepartment of Internal Medicine and Cardiology, Asklepios Klinikum Schildautal, Seesen, Germany.
Hendrik BonnemeierLife Sciences, University of Applied Sciences Bremerhaven, An der Karlstadt 8, Bremerhaven, 27568, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCardiac implantable electronic device (CIED) infection remains one of the most serious complications of device therapy, causing significant morbidity, mortality, healthcare utilization, and costs. Despite advances in device technology and preventive strategies, infection rates have not declined and may be increasing. This review summarizes current evidence on CIED infection prevention and device pocket management, with a focus on risk-based prevention, procedural strategies, and emerging technologies. RECENT

findingsIncreasing evidence supports individualized infection-prevention strategies based on patient-, procedure-, and device-related risk factors. Contemporary approaches extend beyond peri-procedural antibiotic prophylaxis and include structured risk stratification, optimization of modifiable risk factors, meticulous pocket management, prevention of pocket hematoma formation, taurolidine containing adjuncts and selective use of antibacterial technologies such as absorbable antibiotic envelopes. Novel device platforms including leadless pacemakers, subcutaneous and extravascular implantable cardioverter-defibrillators, and conduction system pacing may further reduce infectious burden in selected patients. Emerging technologies including antimicrobial biomaterials, artificial intelligence-assisted risk prediction, and digital wound surveillance may facilitate precision-based infection prevention. CIED infection prevention increasingly requires a comprehensive and individualized approach that addresses the entire contamination - biofilm - infection pathway. Contemporary prevention strategies integrate patient optimization, procedural excellence, pocket management, and selective use of adjunctive technologies. Future advances are likely to shift infection prevention toward precision-based interventions tailored to individual patient risk profiles and device requirements.

Indexed as

Defibrillators, ImplantablePacemaker, ArtificialProsthesis-Related InfectionsAnti-Bacterial AgentsAntibiotic ProphylaxisHumansRisk AssessmentRisk FactorsAnti-Bacterial AgentsAntibacterial envelopeBiofilmCardiac implantable electronic devicesCIED infectionInfection preventionLeadless pacemakerPocket managementPrecision medicineRisk stratificationSubcutaneous ICD

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.