ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Beyond the surface: a comprehensive review of corneal endotheliitis.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Corneal endotheliitis can present with various manifestations, including corneal edema, keratic precipitates, anterior chamber reaction, limbal injection, neovascularization, and elevated intraocular pressure. Several infectious (i.e., viruses, bacteria, fungi) and non-infectious factors (i.e., iatrogenic, systemic diseases, and medications) can contribute to the development of corneal endotheliitis. The anterior chamber-associated immune deviation mechanism is suggested to be activated in the condition. Herein, suppression of cell-mediated immunity may facilitate the proliferation of pathogens, e.g., viruses, within the corneal endothelium, impairing the cells' function and resulting in edema. Treatment options vary due to the exact etiology of the disease; depending on this, steroids, antiviral medications, antibiotics, or antifungals can be prescribed.Accurate and prompt identification of the underlying etiology is crucial in the management of the disease and in achieving optimal visual outcomes. Ophthalmologists should maintain a broad differential diagnosis for patients with suspected endotheliitis and use appropriate diagnostic and therapeutic strategies. Furthermore, future research should unravel the pathophysiological mechanism associated with this condition.
Indexed as
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42878789What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.