Evidence map›Paper›PMID 42877930›Full record

ArticleTaiwan journal of ophthalmology

Retinal vasculature changes after 0.125% atropine treatment in children with myopia measured using optical coherence tomography angiography: A pilot study.

Yao-Chi Huang, Lan-Hsin Chuang, Ling Yeung, Hung-Chi Chen, Tsung-Hsien Tsai, Nan-Kai Wang, Po-Chun Chang, Yih-Shiou Hwang, Wei-Chi Wu, Chi-Chun Lai and 1 more

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Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yao-Chi HuangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Lan-Hsin ChuangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ling YeungCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Hung-Chi ChenCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tsung-Hsien TsaiCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Nan-Kai WangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Po-Chun ChangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yih-Shiou HwangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wei-Chi WuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chi-Chun LaiCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chun-Fu LiuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The study assessed the microvascular changes in the retina after the use of 0.125% atropine in children with myopia and the association between retinal microvascular changes and the effects of myopia treatment. Materials and Methods: This is a prospective cohort study. Children with myopia aged 5-18 years old were included in the study. Retina microvascular parameters were measured with spectral domain optical coherence tomography (OCT) and OCT angiography devices during the follow-up. The main outcome measurements include vessel density of the superficial vascular plexus (SVP), deep vascular plexus, and axial length (AL). Results: A total of 64 eyes of 36 patients were included. A significant decrease in parafoveal vessel density of the SVP was observed in the first 3 months ( Conclusion: These results suggest that 0.125% atropine might induce changes in the retina vasculature in children with myopia and that these changes might correlate with myopia progression. Nevertheless, as a pilot study, this result may need to be confirmed in larger studies.

Indexed as

Atropinemyopiaoptical coherence tomography angiographyretinavessel density

Identifiers

PMID42877930
PMCPMC13668172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.