ArticleTaiwan journal of ophthalmology
Comparing optical coherence tomography angiography biomarker for primary open-angle glaucoma and normal tension glaucoma progression in different stage.
Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare peripapillary and parafoveal microvasculature between primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG) at different disease stages using optical coherence tomography angiography (OCTA). MATERIALS AND
methodsThis retrospective study classified eyes into early, moderate, or severe visual field defect based on Hodapp-Parrish-Anderson criteria. OCTA was used to assess radial peripapillary capillaries (RPCs), retinal nerve fiber layer (RNFL), parafoveal vessel density, and ganglion cell complex thickness. Global and sectoral parameters were compared between POAG and NTG, with subgroup analysis by disease severity.
resultsIn early-stage glaucoma, global RNFL thickness was significantly lower in NTG eyes (87.5 ± 11.3 µm) compared to POAG eyes (92.4 ± 10.5 µm,
conclusionThe microvasculature in the sectoral peripapillary and parafoveal regions shows significant differences between POAG and NTG across various stages. This suggests that the mechanisms underlying these glaucoma subtypes may differ at different stage.
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