Evidence map›Paper›PMID 42877911›Full record

ArticleACG case reports journal2026

Transplant-Free Recovery in Wilson Disease-Associated Acute Liver Failure.

Hakan Demiröz, Yusuf Bünyamin Ketenci, Mehmet Akca, Ufuk Avcıoğlu, Ahmet Bektaş

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hakan DemirözDepartment of Gastroenterology, Ondokuz Mayıs University, Samsun, Turkey.ORCID https://orcid.org/0000-0002-1713-7682
Yusuf Bünyamin KetenciDepartment of Gastroenterology, Ondokuz Mayıs University, Samsun, Turkey.ORCID https://orcid.org/0000-0003-0372-9166
Mehmet AkcaDepartment of Gastroenterology, Ondokuz Mayıs University, Samsun, Turkey.ORCID https://orcid.org/0000-0002-1507-1851
Ufuk AvcıoğluDepartment of Gastroenterology, Ondokuz Mayıs University, Samsun, Turkey.ORCID https://orcid.org/0000-0001-6905-4494
Ahmet BektaşDepartment of Gastroenterology, Ondokuz Mayıs University, Samsun, Turkey.ORCID https://orcid.org/0000-0001-7026-9353

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wilson disease-associated acute liver failure carries high mortality without urgent liver transplantation. Diagnosis is challenging when classical signs like Kayser-Fleischer rings are absent. We report a 28-year-old woman presenting with Wilson disease-associated acute liver failure characterized by Coombs-negative hemolytic anemia, profound hyperbilirubinemia, low alkaline phosphatase, and a New Wilson Index score of 14. Despite predicting poor transplant-free survival, she achieved complete clinical and biochemical recovery following aggressive copper-removal therapy using chelation, zinc, therapeutic plasma exchange, and continuous renal replacement therapy. This case demonstrates that early combined extracorporeal liver support can successfully bridge patients to recovery, potentially obviating liver transplantation.

Indexed as

acute liver failurecontinuous renal replacement therapyNew Wilson Indextherapeutic plasma exchangeWilson disease

Identifiers

PMID42877911
PMCPMC13668288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.