ReviewThe Journal of clinical and aesthetic dermatology2026
Curcumin (
Review in The Journal of clinical and aesthetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurcumin (CUR), the principal polyphenol in
methodsA targeted PubMed search was conducted using a combination of the following keywords: "curcumin," "turmeric," and "dermatology." Only articles in English and relevant to this review were included. Additional articles were included through citation tracking and the authors' clinical expertise.
resultsThe search yielded 375 results, and 94 articles and 2 webpages were included based on the inclusion and exclusion criteria. DISCUSSION: CUR modulates multiple intracellular pathways, resulting in reduced pro-inflammatory cytokine expression, improved oxidative balance, and enhanced tissue repair. Despite an extremely favorable safety profile, the clinical use of CUR remains limited by poor bioavailability; however, newer formulations, including US Food and Drug Administration-recognized medical foods, have substantially improved absorption and product consistency. Clinically, CUR has shown immunomodulatory and anti-inflammatory effects applicable to cutaneous conditions including psoriasis, atopic dermatitis, and photodamage and has exhibited antimicrobial activity in acne. Aesthetically, CUR reduces melanogenesis and provides firming effects by limiting oxidative stress and matrix metalloproteinase activity. Regeneratively, it modulates key longevity-associated pathways involved in cellular senescence, wound healing, and anti-aging.
conclusionCUR represents a safe and multifaceted agent with clinical, aesthetic, and regenerative dermatologic benefits. Emerging medical food formulations offer improved bioavailability and product consistency, though larger clinical trials are needed to define optimal dosing and long-term efficacy.
Indexed as
Identifiers
42877871PMC13668093What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.