Evidence map›Paper›PMID 42877869›Full record

ArticleCureus2026

From Trauma to Tumour: Incidental Giant Left Adrenal Myelolipoma in Congenital Adrenal Hyperplasia.

Emily M Mayar, Anna Crown, Sing Y Sim

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily M MayarEndocrinology, University Hospitals Sussex NHS Foundation Trust, Brighton, GBR.
Anna CrownEndocrinology, University Hospitals Sussex NHS Foundation Trust, Brighton, GBR.
Sing Y SimEndocrinology, University Hospitals Sussex NHS Foundation Trust, Brighton, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenal myelolipomas are rare, benign tumours composed of mature adipose and haematopoietic tissue. Patients with congenital adrenal hyperplasia (CAH) are predisposed to their development, with chronic adrenocorticotropic hormone (ACTH) hypersecretion secondary to impaired cortisol synthesis thought to be the principal driver of myelolipoma formation in this population. A 49-year-old female with known CAH presented to the emergency department following a stab wound to the abdomen. Computed tomography (CT) incidentally identified a 12 cm encapsulated left adrenal lesion consistent with a giant myelolipoma. Despite reported adherence to hydrocortisone and fludrocortisone replacement therapy, persistently elevated adrenal steroid precursors and plasma renin levels suggested suboptimal glucocorticoid control. Following multidisciplinary team (MDT) review, the patient was offered a left adrenalectomy given the lesion size (>10 cm) and concerns regarding the risk of spontaneous haemorrhage. This case underscores the importance of systematic imaging review beyond the primary indication for scanning, and the value of optimising biochemical monitoring and considering adrenal imaging in selected high-risk CAH patients.

Indexed as

21-hydroxylase deficiencyacth hypersecretionadrenalectomyadrenal incidentalomaadrenal myelolipomacongenital adrenal hyperplasia

Identifiers

PMID42877869
PMCPMC13668015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.