Evidence map›Paper›PMID 42877820›Full record

ArticleJournal of blood medicine2026

Hepatitis A-Associated Very Severe Aplastic Anemia in a Young Adult Female: A Case Report.

Taher A Alhaddad, Ahmed Alsaffar, Bashair Alnemer, Lojain Alsahman Ii, Reda Aleid, Shahab Ahmed Alsuliman Snr

Abstract readCase Reports
In one paragraph

Article in Journal of blood medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Taher A AlhaddadDepartment of Internal Medicine, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0009-0002-1209-0106
Ahmed AlsaffarDepartment of Internal Medicine, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0000-0002-7771-308X
Bashair AlnemerDepartment of Internal Medicine, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0009-0009-4991-8940
Lojain Alsahman IiDepartment of Hematology, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0009-0007-0575-6519
Reda AleidDepartment of Hematology, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0009-0000-6652-5895
Shahab Ahmed Alsuliman SnrDepartment of Infectious Diseases, Dammam Medical Complex, Dammam, Saudi Arabia.ORCID 0000-0003-2361-3670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hepatitis‑associated aplastic anemia (HAAA) is a rare but life‑threatening immune‑mediated complication of acute viral hepatitis, and hepatitis A virus is an uncommon cause of this syndrome. Case Presentation: We report the case of a 24‑year‑old woman who developed acute hepatitis A followed by rapidly progressive pancytopenia fulfilling the criteria for very severe aplastic anemia. Her clinical course was complicated by febrile neutropenia, transfusion dependence, gastrointestinal bleeding, and Conclusion: Aplastic anemia following acute hepatitis A infection is rare but potentially fatal. Early recognition of cytopenias during or following acute hepatitis, prompt bone marrow evaluation, and urgent hematology referral is essential for timely definitive treatment and improved outcomes.

Indexed as

bone marrow failurehepatitis-associated aplastic anemiahepatitis A viruspancytopeniavery severe aplastic anemia

Identifiers

PMID42877820
PMCPMC13664683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.