ArticleRisk management and healthcare policy2026
Modifiable Lifestyle Risk Factors for Lower Extremity Arteriosclerosis Obliterans in a High-Risk Population: A Retrospective Case-Control Study.
Article in Risk management and healthcare policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To identify specific modifiable lifestyle risk factors associated with lower extremity arteriosclerosis obliterans (LEASO) in a high-risk screening population to guide targeted primary prevention. Methods: This retrospective case-control study enrolled 300 individuals at high risk for LEASO from a tertiary hospital in Shanxi Province, China. Baseline lifestyle habits were assessed using the Lifestyle and Lower Extremity Vascular Health Questionnaire, and participants were followed for 2 years. Multivariate logistic regression was used to analyze the relationship between lifestyle habits and LEASO incidence. Results: Multivariate logistic regression identified smoking (OR = 2.289, 95% CI: 1.254-4.178), high-salt diet (OR = 2.040, 95% CI: 1.334-3.120), high-fat diet (OR = 1.988, 95% CI: 1.232-3.239), high-cholesterol diet (OR = 1.571, 95% CI: 1.131-2.183), staying up late (OR = 1.826, 95% CI: 1.119-2.980), and prolonged sitting (OR = 2.259, 95% CI: 1.034-4.937) as significant independent risk factors (all P < 0.05). Conclusion: In high-risk populations, specific lifestyle factors-particularly smoking, prolonged sitting, and poor dietary habits-are strongly associated with LEASO. These findings highlight the critical need for behavior-targeted community interventions to mitigate peripheral vascular disease progression.
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