Evidence map›Paper›PMID 42877708›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Lifestyle,

Shiwen Li, Yu Yu, Vanessa Cunanan, Kamal Masaki, G Webster Ross

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shiwen LiDepartment of Public Health Sciences Thompson School of Social Work & Public Health, University of Hawaii at Manoa Honolulu Hawai'i USA.
Yu YuCenter for Health Policy Research University of California Los Angeles California USA.
Vanessa CunananDepartment of Public Health Sciences Thompson School of Social Work & Public Health, University of Hawaii at Manoa Honolulu Hawai'i USA.
Kamal MasakiDepartment of Research Kuakini Medical Center Honolulu Hawai'i USA.
G Webster RossDepartment of Geriatric Medicine John A. Burns School of Medicine, University of Hawaii at Manoa Honolulu Hawai'i USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe assessed whether lifestyle, race/ethnicity, and apolipoprotein E gene (

methodsThis secondary cohort analysis used data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study and the Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN) cohort. Cognitively unimpaired adults aged 65 to 85 years (

resultsAmong Non-Hispanic White participants, higher HLI was associated with fewer depressive symptoms, sufficient sleep was associated with smaller ε4-related increases in anxiety, and excessive alcohol use amplified ε4-related cognitive decline. Among participants from other racial/ethnic groups, walking and higher HLI were associated with more favorable anxiety/depression trajectories. DISCUSSION: Adequate sleep, limited alcohol, walking, and no smoking may support emotional and cognitive health.

Indexed as

amyloid positron emission tomographyAnti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease Studyapolipoprotein E with ε4 allelehealthy lifestylepreclinical Alzheimer's diseaserace/ethnicity

Identifiers

PMID42877708
PMCPMC13662955

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.