Evidence map›Paper›PMID 42877690›Full record

ArticleFrontiers in immunology2026

Survival after hematopoietic cell transplantation in children and adults in four decades of experience: nationwide study.

Małgorzata Dudkiewicz, Anna Łęczycka, Małgorzata Sobczyk-Kruszelnicka, Grzegorz Helbig, Kamil Wieczorek, Jan Kulkowski, Sebastian Giebel, Tomasz Czerw, Jan Maciej Zaucha, Andrzej Hellmann and 55 more

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Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

65 authors.

Małgorzata Dudkiewicz *Polish Transplant Coordinating Center Poltransplant CBMDR, Warsaw, Poland.
Anna Łęczycka *Polish Transplant Coordinating Center Poltransplant CBMDR, Warsaw, Poland.
Małgorzata Sobczyk-KruszelnickaDepartment of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Grzegorz HelbigDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland.
Kamil WieczorekDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland.
Jan KulkowskiDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland.
Sebastian GiebelDepartment of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Tomasz CzerwDepartment of Bone Marrow Transplantation and Onco-Hematology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice, Poland.
Jan Maciej ZauchaDepartment of Hematology, Transplantology and Cell Therapies, Medical University of Gdańsk and University Clinical Center, Gdańsk, Poland.
Andrzej HellmannDepartment of Hematology, Transplantology and Cell Therapies, Medical University of Gdańsk and University Clinical Center, Gdańsk, Poland.
Dorota ZielińskaDepartment of Hematology, Transplantology and Cell Therapies, Medical University of Gdańsk and University Clinical Center, Gdańsk, Poland.
Lidia GilDepartment of Hematology, Poznan University of Medical Sciences, Poznan, Poland.
Agnieszka Nowak-PotoczekDepartment of Hematology, Poznan University of Medical Sciences, Poznan, Poland.
Agnieszka WołoszynDepartment of Hematology, Poznan University of Medical Sciences, Poznan, Poland.
Patrycja Mensah-GlanowskaDepartment of Hematology, University Hospital Kraków, Kraków, Poland.
Joanna SkórzyńskaDepartment of Hematology, University Hospital Kraków, Kraków, Poland.
Tomasz WróbelDepartment of Hematology, Cellular Therapies and Internal Medicine, Wrocław Medical University, Wroclaw, Poland.
Anna CzyżDepartment of Hematology, Cellular Therapies and Internal Medicine, Wrocław Medical University, Wroclaw, Poland.
Paula Jabłonowska-BabijDepartment of Hematology, Cellular Therapies and Internal Medicine, Wrocław Medical University, Wroclaw, Poland.
Krzysztof KałwakDepartment of Pediatric Hematology/Oncology and BMT, Wrocław Medical University, Wroclaw, Poland.
Marek UssowiczDepartment of Pediatric Hematology/Oncology and BMT, Wrocław Medical University, Wroclaw, Poland.
Agnieszka CieniawaDepartment of Pediatric Hematology/Oncology and BMT, Wrocław Medical University, Wroclaw, Poland.
Jarosław DybkoLower Silesia Centre of Oncology, Pulmonology, and Hematology; Department of Oncology and Hematology, Wroclaw University of Science and Technology, Wrocław, Poland.
Natalia WinciorekLower Silesia Centre of Oncology, Pulmonology, and Hematology; Department of Oncology and Hematology, Wroclaw University of Science and Technology, Wrocław, Poland.
Joanna Romejko-JarosińskaDepartment of Lymphoid Malignancies, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Kazimierz HałaburdaInstitute of Hematology and Transfusion Medicine, Warsaw, Poland.
Jeremi SzypnickiInstitute of Hematology and Transfusion Medicine, Warsaw, Poland.
Piotr RzepeckiDepartment of Internal Medicine and Hematology Military Institute of Medicine - National Research Institute, Warsaw, Poland.
Anna OwczarekDepartment of Internal Medicine and Hematology Military Institute of Medicine - National Research Institute, Warsaw, Poland.
Agnieszka WierzbowskaDepartment of Hematology, Medical University, Łódź, Poland.
Olga Grzybowska-IzydorczykDepartment of Hematology, Medical University, Łódź, Poland.
Grzegorz BasakDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Iwona MarszałekDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Jacek WachowiakDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznań, Poland.
Katarzyna DerwichDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznań, Poland.
Agnieszka Sobkowiak-SobierajskaDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznań, Poland.
Marek HusDepartment of Hematology and Transplantology, Medical University, Lublin, Poland.
Magdalena KoziołDepartment of Hematology and Transplantology, Medical University, Lublin, Poland.
Robert DębskiDepartment of Pediatric Hematology, Oncology, Immunology and Transplantology; Collegium Medicum Nicolaus Copernicus University Torun, Bydgoszcz, Poland.
Krzysztof CzyżewskiDepartment of Pediatric Hematology, Oncology, Immunology and Transplantology; Collegium Medicum Nicolaus Copernicus University Torun, Bydgoszcz, Poland.
Jolanta GoździkTransplantation Center University Children's Hospital in Krakow. Department Clinical Immunology and Transplantation Medical College Jagiellonian University, Krakow, Poland.
Agnieszka DłużniewskaTransplantation Center University Children's Hospital in Krakow. Department Clinical Immunology and Transplantation Medical College Jagiellonian University, Krakow, Poland.
Jacek KrzanowskiBrzozow Oncology Center, Brzozów, Poland.
Jarosław KopiczakBrzozow Oncology Center, Brzozów, Poland.
Wojciech LegiećDepartment of Hematology and Bone Marrow Transplantation, St. John of Dukla Oncology Center, Lublin, Poland.
Adrianna WieluńskaDepartment of Hematology and Bone Marrow Transplantation, St. John of Dukla Oncology Center, Lublin, Poland.
Katarzyna DrabkoDepartment of Pediatric Hematology, Oncology and Transplantology Medical University of Lublin, Lublin, Poland.
Teresa Greczkowska-ChmielDepartment of Pediatric Hematology, Oncology and Transplantology Medical University of Lublin, Lublin, Poland.
Bogusław MachalińskiDepartment of Hematology and Bone Marrow Transplantation, Pomeranian Medical University, Szczecin, Poland.
Sławomir MilczarekDepartment of Hematology and Bone Marrow Transplantation, Pomeranian Medical University, Szczecin, Poland.
Wojciech HomendaDepartment of Hematology and Bone Marrow Transplantology, Regional Hospital; Institute of Health Sciences, Pomeranian University of Słupsk, Słupsk, Poland.
Rafał MoraczyńskiDepartment of Hematology and Bone Marrow Transplantology, Regional Hospital; Institute of Health Sciences, Pomeranian University of Słupsk, Słupsk, Poland.
Grzegorz CharlińskiDepartment of Hematology, Nicolaus Copernicus Hospital, Toruń, Poland.
Violetta KalinowskaDepartment of Hematology, Nicolaus Copernicus Hospital, Toruń, Poland.
Iwona MalinowskaDepartment of Oncology, Pediatric Hematology, Clinical Transplantology, Pediatrics and Rare Disorders, Medical University of Warsaw, Warsaw, Poland.
Michał RomiszewskiDepartment of Oncology, Pediatric Hematology, Clinical Transplantology, Pediatrics and Rare Disorders, Medical University of Warsaw, Warsaw, Poland.
Katarzyna Brzeźniakiewicz-JanusDepartment of Hematology, Oncology and Radiotherapy; University of Zielona Góra, Multi-Specialist Hospital in Gorzów Wielkopolski, Gorzów Wielkopolski, Poland.
Katarzyna KoperDepartment of Hematology, Oncology and Radiotherapy; University of Zielona Góra, Multi-Specialist Hospital in Gorzów Wielkopolski, Gorzów Wielkopolski, Poland.
Mirosław MarkiewiczDepartment of Hematology, Faculty of Medicine, University Clinical Hospital, Collegium Medicum, University of Rzeszów, Rzeszow, Poland.
Rafał PeszukDepartment of Hematology, Faculty of Medicine, University Clinical Hospital, Collegium Medicum, University of Rzeszów, Rzeszow, Poland.
Marcin PasiarskiDepartment of Hematology, Holy Cross Cancer Centre; Department of Immunology, Jan Kochanowski University, Kielce, Poland.
Jarosław CzerwińskiPolish Transplant Coordinating Center Poltransplant CBMDR, Warsaw, Poland.
Artur KamińskiPolish Transplant Coordinating Center Poltransplant CBMDR, Warsaw, Poland.
Wiesław Wiktor JędrzejczakDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Jan StyczyńskiDepartment of Pediatric Hematology, Oncology, Immunology and Transplantology; Collegium Medicum Nicolaus Copernicus University Torun, Bydgoszcz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to provide a comprehensive nationwide analysis of the development of hematopoietic cell transplantation (HCT) in Poland in the years 1984-2024, including temporal trends in transplant activity, transplant and donor types, stem cell sources, and patient survival. Methods: Centers reported basic data on all HCTs performed from the beginning of their activity up to the end of 2024. Survival data were identified in national registry. Results: The total number of HCTs was 30,812, including 40.1% allo-HCTs and 59.9% auto-HCTs. Pediatric centers performed 22.8% of all transplants; including 5.8% all auto-HCTs and 23.3% all allo-HCTs. Overall survival for children after allo-HCT was: 70.1% at 5 years and 67.2% at 10 years, while after auto-HCT was 57.1% at 5 years and 49.0% at 10 years. Overall survival for adults after allo-HCT was: 55.1% at 5 years and 49.0% at 10 years, while after auto-HCT was 73.5% at 5 years and 64.5% at 10 years. 10-years overall survival for children after allo-HCT with respect to donor type was 70.5% for MSD-HCT; 67.2% for UD-HCT; 44.8% for haplo-HCT; while for adults 49.5% for MSD-HCT; 49.6% for UD-HCT; 38.8% for haplo-HCT. Higher survival rates were observed in children <10 vs >10 years, and in adults <25 years vs >25 years. 10-years overall survival after HCT improved with subsequent time periods both in children and adults. Conclusions: Over a period of 40 years, increasing survival rates of allogeneic and autologous HCT are observed. There is an advantage in survival of younger patients.

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedPolandRegistriesTransplantation, AutologousTransplantation, HomologousYoung Adultadultschildrenhematopoietic cell transplantationlong-term follow-upsurvival

Identifiers

PMID42877690
PMCPMC13663881

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