Evidence map›Paper›PMID 42877649›Full record

ArticleJPGN reports2026

Severe constipation-associated postprandial abdominal pain in a pregnant native-liver biliary atresia survivor after Kasai portoenterostomy: A case report.

Akram Alnounou, Ajay Katwala, Mohammad Alabbas, Bisher Sawaf, Arghyadeep Ganguly, EzzElDien A Ibrahim, Fnu Vikash

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akram AlnounouDepartment of Internal Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.ORCID https://orcid.org/0009-0002-5657-1139
Ajay KatwalaCollege of Health Sciences Marquette University Milwaukee Wisconsin USA.ORCID https://orcid.org/0009-0001-9238-1677
Mohammad AlabbasDepartment of Gastroenterology, Hepatology, and Nutrition Cleveland Clinic Cleveland Ohio USA.ORCID https://orcid.org/0000-0001-7981-2682
Bisher SawafDepartment of Internal Medicine University of Toledo Medical Center Toledo Ohio USA.ORCID https://orcid.org/0000-0001-6751-619X
Arghyadeep GangulyDepartment of Internal Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.ORCID https://orcid.org/0000-0002-0078-658X
EzzElDien A IbrahimDepartment of Medicine University of Missouri-Columbia Columbia Missouri USA.ORCID https://orcid.org/0000-0002-9403-5970
Fnu VikashDepartment of Gastroenterology, Hepatology, and Nutrition Cleveland Clinic Cleveland Ohio USA.ORCID https://orcid.org/0000-0001-6063-1558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 18-year-old woman with congenital biliary atresia status post Kasai portoenterostomy and magnetic resonance imaging-reported chronic liver disease presented at 32 weeks' gestation with 6 weeks of worsening postprandial epigastric/right upper quadrant pain, nausea, and poor oral intake. Evaluation showed preserved hepatic synthetic function and no demonstrated clinically significant portal hypertension. Endoscopy excluded esophageal and gastric varices, computed tomography showed no imaging evidence of pancreatitis, biliary obstruction, or other acute intra-abdominal pathology, computed tomography angiography excluded mesenteric ischemia, and gastric emptying scintigraphy excluded gastroparesis. Nonreassuring fetal surveillance prompted preterm induction at approximately 33 weeks 4 days. Postpartum symptoms persisted, and imaging review identified severe constipation with rectal impaction/fecalization as the dominant treatable contributor. This case broadens the peripartum phenotype reported in native-liver biliary atresia survivors by emphasizing constipation-associated postprandial abdominal pain, poor oral intake, nutritional risk, and medication-related bowel dysfunction rather than variceal bleeding or hepatic decompensation alone.

Indexed as

chronic liver diseasefecal impactionperipartum careportal hypertension

Identifiers

PMID42877649
PMCPMC13662888

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.