Evidence map›Paper›PMID 42877571›Full record

ArticleChem2026

Site-selective Au(III)-mediated metalloenzyme conjugations.

Nima Adhami, Michael J P Rebelo, Pathorn H Teptarakulkarn, Sofia H Ando, Eileen J Olivares, Thomas Louis-Goff, Aldo J Muñoz, Varun Tej Raviprolu, Michael R Sawaya, Doyeon Han and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Nima AdhamiDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Michael J P RebeloDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Pathorn H TeptarakulkarnDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Sofia H AndoDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Eileen J OlivaresDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Thomas Louis-GoffDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Aldo J MuñozDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Varun Tej RaviproluDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Michael R SawayaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Doyeon HanDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Itzel P VacaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Niko W VlahakisDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Songrong QuDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Tyler A KerrDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Reanne J CoutinhoDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Rachel R Ogorzalek LooDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Joseph A LooDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Hannah S ShafaatDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Jose A RodriguezDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.
Alexander M SpokoynyDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 611 Charles E. Young Drive East, Los Angeles, California, 90095, United States.

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6M
Inorganic Chemistry Tools for Bioconjugation, Recognition and ImagingR35GM124746 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Alexander Michael Spokoyny · 2017 to 2026
$4.0M
Micro Electron Diffraction of Toxic and/or Infectious Macromolecular NanoassembliesR35GM128867 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jose Alfonso Rodriguez · 2018 to 2026
$3.1M
Advancing Mass Spectrometry Analyses of Proteins, Assemblies, and ProteoformsR35GM145286 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Joseph A Loo · 2022 to 2026
$1.9M
NMR Console and Prodigy CryoProbeS10OD028644 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2021 to 2021
$600k
Circular Dichroism SpectrometerS10OD028491 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2020 to 2020
$100k
NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R35 GM124746NIGMS NIH HHS R35 GM128867NIGMS NIH HHS R35 GM145286NIH HHS S10 OD028491NIH HHS S10 OD028644
6 · The paper itself

Abstract

Herein, we introduce an operationally simple approach for the direct covalent modification of metalloenzymes via Au(III)-mediated

Indexed as

Au(III)backgroundlessconjugationcysteinemetalloenzymerapid kineticsrubredoxinsite-selective

Identifiers

PMID42877571
PMCPMC13662807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.