Evidence map›Paper›PMID 42877557›Full record

ArticleChina CDC weekly2026

Shifting Burden of Neural Tube Defects from Early-Life Mortality to an Aging Population Living with Disability - China, 1990-2023.

Yuwei Wu, Xiaoqian Jia, Lingzhang Wang, Xinyue Lin, Yali Zhang, Le Zhang, Zhiwen Li, Zhiyong Zou, Jufen Liu

Abstract read
In one paragraph

Article in China CDC weekly, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuwei WuInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Xiaoqian JiaInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Lingzhang WangInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Xinyue LinInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Yali ZhangInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Le ZhangInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Zhiwen LiInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.
Zhiyong ZouInstitute of Child and Adolescent Health, School of Public Health, Peking University, National Health Commission Key Laboratory of Reproductive Health, Beijing, China.
Jufen LiuInstitute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: The burden of neural tube defects (NTDs) has declined with folic acid supplementation and fortification, but comprehensive all-age estimates are lacking. What is added by this report?: Using data from the Global Burden of Disease Study 2023, we assessed the all-age NTD burden in China during 1990-2023. Incidence, mortality, and disability-adjusted life year (DALY) rates declined significantly, whereas prevalence increased among adults aged ≥50 years and DALY rates increased among those aged ≥75 years, indicating a shift from early-life mortality to disability in an aging population. What are the implications for public health practice?: Life-course care should combine primary prevention, long-term rehabilitation and multidisciplinary management for people with NTDs.

Indexed as

Burden of diseaseNeural tube defectsTemporal trend

Identifiers

PMID42877557
PMCPMC13662706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.