ReviewJournal of contemporary brachytherapy2026
Three-dimensional-printed template-assisted image-guided brachytherapy for cervical cancer: Technology, dosimetry, and clinical implementation.
Review in Journal of contemporary brachytherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Three-dimensional (3D)-printed templates have emerged as practical tools to reduce geometric uncertainty and workflow variability in free-hand intracavitary/interstitial (IC/IS) brachytherapy for cervical cancer. This narrative review aimed to summarize contemporary evidence on 3D-printed templates and applicators, focusing on technology, dosimetry, clinical outcomes, and practical implementation within modern image-guided brachytherapy programs. Material and methods: A narrative literature review with structured search and evidence mapping elements was performed using PubMed and PubMed Central to identify clinical, dosimetric, and technical studies reporting on 3D-printed templates or applicators for cervical or gynecologic brachytherapy between January 2020 and April 2026. The final search was updated on April 28, 2026. Search terms combined cervical cancer, brachytherapy, and 3D printing concepts. Human studies describing device design, imaging and planning approaches, dosimetry, clinical outcomes, or workflow metrics were included, while reference lists of key articles and guidelines were screened to capture influential pre-3D printing mould and hybrid IC/IS series. Data from eligible reports were summarized in structured tables and synthesized qualitatively by theme. Results: Current evidence suggests that 3D-printed templates and applicators can improve the reproducibility of intracavitary/interstitial implantation, and facilitate individualized high-dose-rate or low-dose-rate brachytherapy in anatomically complex primary and recurrent cervical cancer. The reported studies generally showed improved high-risk clinical target volume coverage, higher D Conclusions: Three-dimensional-printed template-assisted brachytherapy represents a clinically relevant strategy for improving implantation reproducibility and supporting individualized image-guided brachytherapy in cervical cancer. Although promising, evidence is still evolving. Wider adoption will require prospective multi-institutional validation, standardized manufacturing and sterilization pathways, robust template-specific quality assurance, and pragmatic implementation models suitable for different clinical settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.