Evidence map›Paper›PMID 42877356›Full record

ArticleBalkan journal of medical genetics : BJMG2026

DNA Methylation and TMPRSS2-ERG Fusion Status in Patients with Prostate Cancer from The Republic of North Macedonia.

A Trifunovski, A Gavrilovska-Brzanov, S Dohchev, J Janculev, D Trajkovski, I Vujicic, G Severova Andreevska, M Ambardjieva, E Dodikj

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Article in Balkan journal of medical genetics : BJMG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A TrifunovskiUniversity Clinic of Urology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
A Gavrilovska-BrzanovUniversity Clinic for Traumatology, Orthopedic Diseases, Anesthesia, Reanimation, Intensive Care and Emergency Centre, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
S DohchevUniversity Clinic of Urology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
J JanculevUniversity Clinic of Urology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
D TrajkovskiUniversity Clinic of Urology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
I VujicicUniversity Clinic of Urology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
G Severova AndreevskaUniversity Clinic of Nephrology, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
M AmbardjievaUniversity Clinic for Surgical Diseases "St. Naum Ohridski, Medical Faculty, University of "Ss. Cyril and Methodius"- Skopje, R. N. Macedonia.
E DodikjDepartment of Internal Medicine, Cardiology Unit, General Hospital-Kumanovo, North Macedonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second leading cause of male deaths in the Western world and the most commonly detected cancer in males. Recent studies have pointed out that DNA methylation and TMPRSS2-ERG fusion transcript, have a high presence among prostate tumor cells. It is estimated that these two molecular mechanisms could be used as potential markers for early detection of malignancy, and/or progression of prostate cancer disease. The study aimed to test the presence of the DNA methylation and TMPRSS2-ERG fusion transcript in patients with prostate cancer, as a baseline database for further genetic examination. This prospective clinical study focused on a random sample of 88 patients with prostate carcinoma. For the detection of methylation status in 26 tumor suppressor genes (

Indexed as

DNA methylationprostate cancerTMPRSS2-ERG

Identifiers

PMID42877356
PMCPMC13667934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.