Evidence map›Paper›PMID 42877256›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2026

Environmental Exposures and Computational Mechanisms in Psychosis Risk: Insights from a Multi-Site Cohort.

Luz Maria Alliende, Victor Pokorny, Benson Ku, Natalie Larson, Gregory P Strauss, L Lauren Ellman, Elaine F Walker, Philip Corlett, Jason Schiffman, Scott W Woods and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Luz Maria AlliendeDepartment of Psychology, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-7648-9215
Victor PokornyDepartment of Psychology, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-1003-0196
Benson KuDepartment of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, 30322, USA.ORCID 0000-0001-6994-8770
Natalie LarsonDepartment of Psychology, Northwestern University, Evanston, IL, 60208, USA.ORCID 0009-0008-3340-9255
Gregory P StraussDepartments of Psychology and Neuroscience, University of Georgia, Athens, GA, 30602, USA.ORCID 0000-0002-7218-5169
L Lauren EllmanDepartment of Psychology & Neuroscience, Temple University, Philadelphia, PA, 19122, USA.
Elaine F WalkerDepartment of Psychology and Program in Neuroscience, Emory University, Atlanta, GA, 30322, USA.ORCID 0000-0002-9798-8101
Philip CorlettDepartment of Psychiatry, Yale University, New Haven, CT, 06519, USA.ORCID 0000-0002-5368-1992
Jason SchiffmanDepartment of Psychological Science, 4201 Social and Behavioral Sciences Gateway, University of California, Irvine, CA, 92697, USA.ORCID 0000-0002-1363-4497
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT, 06519, USA.ORCID 0000-0002-3103-5228
A PowersDepartment of Psychiatry, Yale University, New Haven, CT, 06519, USA.ORCID 0000-0003-3057-5043
S SilversteinDepartments of Psychiatry, Neuroscience and Ophthalmology, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-0699-0960
James WaltzMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, 21228, USA.ORCID 0000-0002-9236-3719
Richard ZinbargDepartment of Psychology, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-2670-6330
Shuo ChenMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, 21228, USA.ORCID 0000-0002-7990-4947
Trevor F WilliamsDepartment of Psychology, Kent State University, Kent, OH, 44240, USA.ORCID 0000-0003-2202-7020
Joshua KenneyDepartment of Psychiatry, Yale University, New Haven, CT, 06519, USA.
James M GoldMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, 21228, USA.ORCID 0000-0002-0109-9554
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0001-9017-5119

Funding

5/5 CAPER: Computerized Assessment of Psychosis RiskR01MH120089 · NIMH · YALE UNIVERSITY · PI CORLETT, PHILIP, WOODS, SCOTT W · 2020 to 2024
$3.1M
1/5 CAPER: Computerized Assessment of ProdromE RiskR01MH120090 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLD, JAMES M. · 2020 to 2024
$2.9M
4/5 CAPER: Computerized assessment of psychosis riskR01MH120092 · NIMH · UNIVERSITY OF GEORGIA · PI STRAUSS, GREGORY P · 2020 to 2024
$2.0M
2/5 CAPER Computerized assessment of psychosis riskR01MH120088 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2020 to 2024
$2.0M
CAPER: Computerized Assessment of Psychosis Risk SupplementR01MH120091 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2020 to 2024
$1.6M
FOLLOW-UP OF THE MULTIMODAL TREATMENT STUDY OF CHILDREN WITH ATTENTION-278012009N01MH012009 · NIMH · UNIVERSITY OF CALIFORNIA, BERK · PI HINSHAW, STEPHEN · 2002 to 2006
–
NIMH NIH HHS N01 MH012009NIMH NIH HHS R01 MH120088NIMH NIH HHS R01 MH120089NIMH NIH HHS R01 MH120090NIMH NIH HHS R01 MH120091NIMH NIH HHS R01 MH120092
6 · The paper itself

Abstract

This study leverages computational psychiatry to examine weighting of perceptual priors and reinforcement learning (RL) as potential pathways connecting environmental stressors to psychosis risk. 506 participants with psychosis-like experiences (PLE) and 328 controls performed behavioral tasks measuring these mechanisms, in addition to symptom assessments. Participants' childhood area social fragmentation and childhood opportunities were also extracted. The association between environmental, computational and clinical measures was assessed, as were mediation pathways. Higher social fragmentation was associated with deficits in RL (

Identifiers

PMID42877256
PMCPMC13664154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.