ArticleArchives of medical science : AMS2026
Daily sedentary behavior exceeding 5 hours is independently associated with MAFLD: a cross-sectional study from NHANES 2017-2020.
Article in Archives of medical science : AMS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant global cause of chronic liver disease, linked to various health issues. Although sedentary behavior (SB) has been associated with MAFLD, an exact upper limit for sedentary time has not been established. This study aimed to investigate the dose-response relationship between sedentary time and MAFLD and identify potential reference values for future research and recommendations. Material and methods: The study analyzed 7,705 participants from the 2017-2020 NHANES cycle, using transient elastography to identify MAFLD and liver fibrosis or cirrhosis. Sedentary time and physical activity levels were determined through a detailed questionnaire, with physical activity classified by official guidelines. Restricted cubic spline and piecewise regression analyses examined the association between sedentary time and MAFLD. Results: Sedentary time demonstrated a linear dose-response relationship with MAFLD ( Conclusions: Prolonged sedentary time is associated with higher odds of MAFLD in US adults. Reducing excessive sedentary behavior may represent a potential strategy for MAFLD prevention, although further longitudinal studies are needed to establish evidence-based sedentary time recommendations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.