ArticleFrontiers in public health2026
Association of a multimodal perioperative nutritional/ERAS care pathway with postoperative infectious complications following radical hysterectomy for cervical cancer: a retrospective nonconcurrent cohort study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Malnutrition is prevalent in women with cervical cancer and may be associated with postoperative infectious complications following radical hysterectomy. Evidence specifically evaluating structured multimodal perioperative nutritional/ERAS care in this population remains limited. Methods: We conducted a single-center retrospective nonconcurrent cohort study of 268 patients who underwent radical hysterectomy for cervical cancer (FIGO stages IA-IIB) between January 2020 and December 2024. Patients who received a structured multimodal perioperative nutritional/ERAS care pathway (NSG, Results: Baseline characteristics were similar in magnitude for measured variables; however, nonsignificant baseline tests were not interpreted as evidence of equivalence or successful matching. The 30-day infectious complication rate was lower in the NSG than in the CG (18.7% vs. 33.6%; unadjusted RR 0.56, 95% CI 0.36-0.85; Conclusion: Receipt of the structured multimodal perioperative nutritional/ERAS care pathway was associated with lower observed odds of 30-day infectious complications and shorter hospitalization. Because the study used a retrospective nonconcurrent comparison and the intervention was bundled, these findings should not be interpreted as proof that nutritional support alone caused the observed differences. Prospective comparative studies are warranted.
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