Evidence map›Paper›PMID 42877007›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Characterization of lower-extremity biomechanics when walking with a hands-free crutch: an integrated experimental and computational analysis.

Md Arifuzzaman Arif, Jaques Reifman, Ankur Padhye, Stacey Meardon, John Willson, Jose E Rubio

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Md Arifuzzaman ArifDepartment of Defense Biotechnology High Performance Computing Software Applications Institute, Defense Health Agency Research & Development, Medical Research and Development Command, Fort Detrick, MD, United States.
Jaques ReifmanDepartment of Defense Biotechnology High Performance Computing Software Applications Institute, Defense Health Agency Research & Development, Medical Research and Development Command, Fort Detrick, MD, United States.
Ankur PadhyeDepartment of Physical Therapy, East Carolina University, Greenville, NC, United States.
Stacey MeardonDepartment of Physical Therapy, East Carolina University, Greenville, NC, United States.
John WillsonDepartment of Physical Therapy, East Carolina University, Greenville, NC, United States.
Jose E RubioDepartment of Defense Biotechnology High Performance Computing Software Applications Institute, Defense Health Agency Research & Development, Medical Research and Development Command, Fort Detrick, MD, United States.

Funding

Environmental Health Perspectives, NIEHS27302C0031 · NIEHS · 2008 to 2008
$1.2M
NIEHS NIH HHS 27302C0031
6 · The paper itself

Abstract

Background: Lower-leg wounds and fractures are some of the most common types of traumatic injuries sustained by U.S. Service members during combat operations. Existing guidelines for on-field management of lower-leg injuries recommend stabilizing the injury and preventing weight-bearing on the affected leg. However, adhering to these recommendations could be challenging because the casualty may need to walk independently to obtain medical care. In this exploratory experimental and computational study, we assessed the biomechanical characteristics of a hands-free crutch device to aid in the mobility of healthy individuals with a hypothetical lower-leg injury. Methods: We conducted an experimental study where we collected anthropometric, body-motion, ground reaction force, spatiotemporal, and electromyography data from 10 young, healthy men who walked with and without the Freedom Leg hands-free crutch on an instrumented treadmill. Using these data, we developed individualized musculoskeletal and finite-element models and computed biomechanical parameters, including joint kinematics and kinetics, muscle activity and metabolic power demand, and tibial stress, for each participant under each of the two walking conditions. We evaluated the suitability of the device by comparing the model-predicted biomechanical parameters between the two conditions. Results: Compared to walking unassisted, walking with the Freedom Leg reduced the peak knee joint reaction force (JRF) by 47%, peak ankle JRF by 98%, and peak tibial stress by 59% in the crutch-supported leg. However, it also introduced unintended consequences in the contralateral leg, increasing the peak hip JRF by 19%, peak hip flexion moment by 50%, and peak hip extension moment by 89% as well as the mean metabolic power demand in representative hip and knee muscles. Conclusion: The Freedom Leg improved mobility by effectively reducing weight-bearing and stabilizing the crutch-supported leg. However, changes in gait patterns also introduced unintended biomechanical consequences in the contralateral leg. This exploratory study provides insights into the biomechanical effects of walking with the Freedom Leg in healthy, young individuals and may inform the development and assessment of future hands-free crutch devices to improve mobility of Service members with lower-leg injuries.

Indexed as

computational modelshands-free crutchleg stabilizationmobility-aid deviceweight-bearing

Identifiers

PMID42877007
PMCPMC13661938

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.