Evidence map›Paper›PMID 42876980›Full record

ArticleJournal of ophthalmic & vision research2026

The Effect of Adjunctive Mitomycin C on Outcomes of Phaco-Viscocanalostomy in Glaucoma: A Randomized Controlled Trial.

Saeed Shokoohi-Rad, Amir Mohammad Karimi, Elham Bakhtiari

Abstract read
In one paragraph

Article in Journal of ophthalmic & vision research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saeed Shokoohi-RadDepartment of Ophthalmology, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Mohammad KarimiDepartment of Ophthalmology, Mashhad University of Medical Sciences, Mashhad, Iran.
Elham BakhtiariDepartment of Pharmacology, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate whether adjunctive intraoperative mitomycin C (MMC) improves intraocular pressure (IOP) control, visual acuity, or medication burden in patients undergoing phaco-viscocanalostomy for moderate to advanced open-angle glaucoma. Methods: This double-masked, parallel-group randomized clinical trial included 92 eyes of 92 patients with medically uncontrolled open-angle glaucoma, who were randomly assigned to undergo phaco-viscocanalostomy with ( Results: After excluding 15 patients (9 lost to follow-up and 6 intraoperative rupture of the trabeculo-Descemet's window), 77 patients (36 in the MMC group and 41 in the control group) were included in the final analysis. No statistically significant differences were found between groups at baseline (all Conclusion: The addition of MMC to phaco-viscocanalostomy did not provide statistically or clinically significant benefits in IOP control (clinically meaningful change defined as

Indexed as

Glaucoma; Intraocular PressureMitomycin CNon-penetrating Glaucoma SurgeryViscocanalostomy

Identifiers

PMID42876980
PMCPMC13662431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.