Evidence map›Paper›PMID 42876878›Full record

ArticleJournal of Alzheimer's disease reports

Smaller pineal volume in Alzheimer's disease than in dementia with Lewy bodies.

Teruyuki Matsuoka, Ryota Kobayashi, Ayu Imai, Kazutaka Sakamoto, Daichi Morioka, Akihito Suzuki, Noriyuki Kimura, Teruaki Masuda, Takuya Ataka, Jin Narumoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Teruyuki MatsuokaDepartment of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.ORCID https://orcid.org/0000-0001-7683-7825
Ryota KobayashiDepartment of Dementia and Clinical Aging Neuroscience, Fujita Health University, Toyoake, Aichi, Japan.
Ayu ImaiDepartment of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
Kazutaka SakamotoDepartment of Psychiatry, Yamagata University School of Medicine, Yamagata City, Yamagata, Japan.
Daichi MoriokaDepartment of Psychiatry, Yamagata University School of Medicine, Yamagata City, Yamagata, Japan.
Akihito SuzukiDepartment of Psychiatry, Yamagata University School of Medicine, Yamagata City, Yamagata, Japan.
Noriyuki KimuraDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, Oita, Japan.
Teruaki MasudaDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, Oita, Japan.ORCID https://orcid.org/0000-0001-9730-3339
Takuya AtakaDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, Oita, Japan.ORCID https://orcid.org/0000-0001-9416-9867
Jin NarumotoDepartment of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.ORCID https://orcid.org/0000-0002-8262-3177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pineal gland volume reduction in Alzheimer's disease (AD) has been reported. Recent findings also indicate an association between pineal volume reduction and dementia with Lewy bodies (DLB). Objective: This study aimed to compare pineal volume between two major neurodegenerative disorders: AD and DLB. Methods: This cross-sectional analysis included patients with AD or DLB who underwent brain magnetic resonance imaging (MRI) and Mini-Mental State Examination (MMSE). AD was diagnosed based on the National Institute on Aging-Alzheimer's Association criteria and confirmed by positive amyloid positron emission tomography. DLB was diagnosed per McKeith et al.'s clinical criteria and confirmed by dopamine transporter single-photon emission computed tomography or Results: Seventy-five patients (AD, 41; DLB, 34; 35 women) were analyzed. PPV was significantly smaller in the AD group than in the DLB group (74.7 ± 18.8 versus 96.0 ± 31.6 mm Conclusions: Pineal volume was smaller in AD than in DLB; this difference may reflect the neuropathological characteristics specific to AD.

Indexed as

Alzheimer's diseaseLewy bodiespineal glandpineal volume reduction

Identifiers

PMID42876878
PMCPMC13662312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.