Evidence map›Paper›PMID 42876831›Full record

ArticleFrontiers in immunology2026

Case Report: Relapse of SLE associated with EBV infection in a patient after CAR-T cell therapy: a clinical case.

Ping Zeng, Qi Ren, Xianfei Gao, Wei Xian, Pui Y Lee, Feng Li, Caihong Xu, Mingqi Zhao, Wenhao Zhou

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ping ZengZunyi Medical University, Zunyi, Guizhou, China.
Qi RenDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Xianfei GaoDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Wei XianDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Pui Y LeeDivision of Immunology, Harvard Medical School, Boston, MA, United States.
Feng LiDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Caihong XuDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Mingqi ZhaoDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.
Wenhao ZhouDepartment of Pediatric, Allergy Immune & Rheumatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangdong Provincial Clinical Research Center for Child Health, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 13-year-old boy with refractory systemic lupus erythematosus (SLE) who achieved drug-free remission after anti-CD19 CAR-T cell therapy, but subsequently experienced Epstein-Barr virus (EBV) reactivation on day 142 after CAR T-cell infusion and peak EBV load was 24,400 IU/mL with a severe drop in platelets to 8×10

Indexed as

Epstein-Barr Virus InfectionsHerpesvirus 4, HumanImmunotherapy, AdoptiveLupus Erythematosus, SystemicAdolescentHumansMaleRecurrenceVirus ActivationCAR- T cell therapychronic active EBV diseaseEpstein–Barr viruspediatric lupusreactivationsystemic lupus erythematosus

Identifiers

PMID42876831
PMCPMC13661498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.