Evidence map›Paper›PMID 42876819›Full record

ArticleFrontiers in oncology2026

Potential involvement of a TLR4-associated CD155/TIGIT pathway in

Xiao Tian, Liming Xu, Yulian Fu, Qiang Qiang, Xue Cao, Jie Wang, Langqing Liu, Bin Ling

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao TianDepartment of Oral and Maxillofacial Oncology Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Liming XuAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Yulian FuAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Qiang QiangAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Xue CaoAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Jie WangAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Langqing LiuAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.
Bin LingAffiliated Stomatology Hospital, Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Accumulating evidence indicates that oral microbiota dysbiosis and periodontal pathogens contribute to the initiation and progression of oral squamous cell carcinoma (OSCC). However, the molecular mechanisms underlying the interaction between Methods: Genes associated with Results: Bioinformatic analysis identified TLR4 as a biologically relevant candidate hub gene potentially linking Conclusion: Our findings suggest that exposure to

Indexed as

CD155oral squamous cell carcinomaPorphyromonas gingivalisTIGITTLR4tumor immune microenvironment

Identifiers

PMID42876819
PMCPMC13661484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.