ArticleFrontiers in oncology2026
Implementation and feasibility of DPYD-guided fluoropyrimidine use in a gastrointestinal oncology clinic at an academic medical center.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Introduction: Genetic variation in Patients and methods: Following education on the clinical utility of DPYD testing, a consensus was reached with the University of Florida Health gastrointestinal oncology clinic on an implementation workflow. Novel clinical decision support (CDS) tools were developed including pre- and post-test inline warnings in chemotherapy treatment plans, clickable dose modification buttons, and a pharmacist-facing alert upon medication verification. Primary outcomes were feasibility metrics including rates and timing of test ordering and sample collection, genotype turnaround time, and clinician response to CDS tools (e.g., FP dose modifications). Results: Discussion: DPYD test implementation with customized CDS tools to support test ordering and FP prescribing in an academic oncology clinic is feasible, with the majority of results returning prior to chemotherapy. Integrating new and unique processes into already established workflows helps achieve timely test ordering and sample collection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.