ArticleFrontiers in medicine2026
Non-invasive assessment of estimated glomerular filtration rate using lens autofluorescence in a population without chronic kidney disease.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The estimated glomerular filtration rate (eGFR) is a vital indicator for monitoring renal health. Limitations caused by invasive serum-based measurement often delay the detection of early-stage renal decline. Advanced glycation end products (AGEs) contribute significantly to renal pathogenesis. This study specifically targets the "pre-clinical" window of renal decline. We investigate whether lens autofluorescence based AGE (LAF-AGE) measurement can serve as a non-invasive early warning indicator for eGFR in an asymptomatic, non chronic kidney disease (CKD) control population, facilitating the possibilities of detection of individuals at risk of future CKD before clinical manifestations. Methods: From an initial pool of 1,937 participants, we excluded those with eGFR < 60 mL/min or albuminuria or microalbuminuria ( Results: LAF-AGEs showed a significant negative association with eGFR in the univariate model ( Conclusion: LAF-AGEs is a valid, practical and non-invasive parameter for eGFR evaluation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.