Evidence map›Paper›PMID 42876569›Full record

ArticleTechnical innovations & patient support in radiation oncology2026

Adverse events in gynaecological radiotherapy: Better Reporting, Interpretation and Dissemination to Generate Evidence (BRIDGE).

Sofia Spampinato, Ewa Burchardt, Magdalena Stankiewicz, Amelia Barcellini, Gemma Eminowicz, Barbara Šegedin, Margit Valgma, Kari Tanderup, Remi Nout, Kathrin Kirchheiner

Abstract read
In one paragraph

Article in Technical innovations & patient support in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofia SpampinatoDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Ewa BurchardtDepartment of Radiotherapy and Gynaecological Oncology, Greater Poland Cancer Center in Poznan, 61-866 Poznań, Poland.
Magdalena StankiewiczBrachytherapy Department, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland.
Amelia BarcelliniDepartment of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.
Gemma EminowiczDepartment of Oncology, University College London Hospital, London, United Kingdom.
Barbara ŠegedinDepartment of Radiotherapy, Institute of Oncology, Ljubljana, Slovenia.
Margit ValgmaRadiotherapy Centre, North Estonia Medical Centre Foundation, Tallinn, Estonia.
Kari TanderupDanish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.
Remi NoutDepartment of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Kathrin KirchheinerDepartment of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate adverse events (AE) reporting is essential in gynaecological radiotherapy, as multimodal approaches become increasingly common. While these strategies improve outcomes, they may increase the risk of complications affecting patients' quality of life. The BRIDGE (Better Reporting, Interpretation and Dissemination to Generate Evidence) initiative aims to improve consistency and understanding in AE assessment across the radiotherapy community. This analysis investigated whether interpretation of the same clinical information leads to variability in AE grading using the Common Terminology Criteria for Adverse Events (CTCAE) v6.0. An interactive poll conducted during an ESTRO webinar used two clinical scenarios. Among 71 attendees, 30 responded to the poll and 23 consented to share their data. Variation in severity scoring was observed, especially for subjective and lower-grade AEs, whereas higher agreement occurred when clinical details aligned with CTCAE terminology. Findings highlight the importance of training, clear clinical context, and integration of patient-reported outcomes to support person-centred care.

Identifiers

PMID42876569
PMCPMC13661216

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.