ArticleFrontiers in medicine2026
Bone marrow cytology as an adjunct tool for post-mortem interval estimation.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Estimating the post-mortem interval (PMI) remains challenging, particularly when external indicators are unreliable. Sternal bone marrow may provide a relatively stable substrate for PMI assessment. Methods: This observational autopsy-based study evaluated sternal bone marrow from 105 medico-legal autopsy cases with known PMI. Giemsa-stained aspirates were graded (1-5) for nuclear and cytoplasmic autolytic changes and grouped into five PMI intervals (<9 h to >27 h). Results: A highly significant association was observed between PMI and cellular degradation ( Discussion: Sternal bone marrow cytology demonstrates a significant time-dependent association with PMI and may serve as a low-cost complementary tool during the early to intermediate post-mortem period. Further studies are required to establish its predictive accuracy and reproducibility.
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