Evidence map›Paper›PMID 42876502›Full record

ArticleiScience2026

NDUFAF2 promotes abdominal aortic aneurysm formation through mitochondrial dysfunction-induced apoptosis.

Haipeng He, Jiaxin Peng, Huining Chen, Yibo Zhang, Songbiao Zhan, Lei Chen, Xue Han, Henghui Yin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haipeng HeDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.
Jiaxin PengDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.
Huining ChenDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.
Yibo ZhangDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.
Songbiao ZhanDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.
Lei ChenDepartment of Vascular Surgery, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang 310011, China.
Xue HanDepartment of Anesthesia, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510235, China.
Henghui YinDepartment of Vascular Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510630, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease closely associated with mitochondrial dysfunction and apoptosis. Here, we found that NDUFAF2 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 2) was significantly upregulated in cultured cells and murine AAA tissues. Knockdown of NDUFAF2

Indexed as

Abdominal aortic aneurysmApoptosisBioinformaticsMitochondrial damageNDUFAF2OPA1

Identifiers

PMID42876502
PMCPMC13661206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.