Evidence map›Paper›PMID 42876446›Full record

ArticleBiochemistry and biophysics reports2026

A single amino acid mutation alters substrate specificity towards l-glucose in a bacterial l-galactose dehydrogenase.

Nana Obara, Chihiro Ito, Keito Kawashita, Mihoko Takenoya, Myoungjin Kim, Shinsaku Ito, Yasuyuki Sasaki, Akira Nakamura, Shunsuke Yajima

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nana ObaraDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Chihiro ItoDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Keito KawashitaDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Mihoko TakenoyaDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Myoungjin KimDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Shinsaku ItoDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Yasuyuki SasakiDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.
Akira NakamuraInstitute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan.
Shunsuke YajimaDepartment of Bioscience, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structure-based mutagenesis was performed to modify the substrate specificity of bacterial l-galactose dehydrogenase from

Indexed as

Enantioselectivityl-Glucose dehydrogenase activitySubstrate specificityX-ray crystallography

Identifiers

PMID42876446
PMCPMC13661200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.