Evidence map›Paper›PMID 42876345›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2026

Structure-activity relationship of Cu(II) and Pd(II) thiosemicarbazone complexes with anticancer and antibacterial properties.

Bartłomiej Rogalewicz, Magdalena Iwan, Marcin Świątkowski, Mariola Michalczuk, Joanna Kubik, Ewelina Humeniuk, Agnieszka Korga-Plewko, Monika Pitucha, Tomasz Boruta, Tomasz Sierański and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bartłomiej RogalewiczInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland.
Magdalena IwanDepartment of Toxicology, Medical University of Lublin, Lublin, Poland.
Marcin ŚwiątkowskiInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland.
Mariola MichalczukIndependent Medical Biology Unit, Medical University of Lublin, Lublin, Poland.
Joanna KubikIndependent Medical Biology Unit, Medical University of Lublin, Lublin, Poland.
Ewelina HumeniukIndependent Medical Biology Unit, Medical University of Lublin, Lublin, Poland.
Agnieszka Korga-PlewkoIndependent Medical Biology Unit, Medical University of Lublin, Lublin, Poland.
Monika PituchaIndependent Radiopharmacy Unit, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
Tomasz BorutaFaculty of Process and Environmental Engineering, Department of Bioprocess Engineering, Lodz University of Technology, Łódź, Poland.
Tomasz SierańskiInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland.
Jakub KubickiInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland.
Sylwia ŚcieszkaInstitute of Fermentation Technology and Microbiology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Łódź, Poland.
Edyta Kordialik-BogackaInstitute of Fermentation Technology and Microbiology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Łódź, Poland.
Agnieszka CzylkowskaInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Łódź, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twelve thiosemicarbazones and 24 corresponding Cu(II) and Pd(II) complexes were synthesised and evaluated for their physicochemical properties and biological activities. Single-crystal X-ray diffraction and mass spectrometry confirmed ligand deprotonation and the formation of neutral ML

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesCopperPalladiumThiosemicarbazonesCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipAnti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesCopperPalladiumThiosemicarbazonesantibacterial activityAnticancer activitycopper(II) complexespalladium(II) complexesstructure–activity relationshipthiosemicarbazones

Identifiers

PMID42876345
PMCPMC13674658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.