Evidence map›Paper›PMID 42875797›Full record

ArticlePediatric rheumatology online journal2026

African recommendations for diagnosis and management of systemic juvenile idiopathic arthritis (sJIA) - a PAFLAR initiative.

Soad Hashad, Angela Nyangore Migowa, Ahmed Seri, Ourida Gacem, Ali Sobh, Hala Etayari, Eman A Almsillati, Angelo Ravelli, Pierre Quartier, Ayodele Faleye and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric rheumatology online journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Soad HashadTripoli Children Hospital, Tripoli, Libya.
Angela Nyangore MigowaDepartment of Paediatrics and Child Health, Aga Khan University Hospital, Nairobi, Kenya. angela.migowa@aku.edu.ORCID http://orcid.org/0000-0002-1146-7963
Ahmed SeriClinical Immunology and Allergy Centre, Royal Care International Hospital / Clinical Immunology and Allergy Department, Soba University Hospital, Khartoum, Sudan.
Ourida GacemDepartment of Pediatrics, Bir Traria Hospital El Biar, University of Algiers 1, Algiers, Algeria.
Ali SobhDepartment of Pediatrics, Faculty of Medicine, Mansoura University Children's Hospital, Mansoura University, Mansoura, Egypt.
Hala EtayariTripoli Children Hospital, Tripoli, Libya.
Eman A AlmsillatiTripoli Children Hospital, Tripoli, Libya.
Angelo RavelliIRCCS Istituto Giannina Gaslini, Genoa, Italy.
Pierre QuartierPediatric Immuno-Hematology and Rheumatology Unit, RAISE Reference Center (ERN RECONNECT), Hopital Universitaire Necker-Enfants Malades, Paris, France.
Ayodele FaleyeDepartment of Pediatrics, Lagos State University, Teatching Hospital, Lagos, Nigeria.
Waleed HassanRheumatology and Rehabilitation Department, Benha University, Banha, Egypt.
Doaa MosadDepartment of Rheumatology & Rehabilitation, Mansoura University Hospitals, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Elisa PalalaneHospital central de Maputo- Mozambique, Maputo, Mozambique.
Temesgen TeferiColleges of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Yaninga Halwani FuseiniTamale Teaching Hospital, Tamale, Ghana.
Mohammed HassanRheumatology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Hanna LishanAddis Ababa University, College of Health Sciences, Addis Ababa, Ethiopia.
Wassila MessadiUniversity Hospital of Issaad Hassani, Algiers, Algeria.
Madeleine NgandeuUniversity of Yaounde, Ngoa-Ekelle, Yaoundé, Cameroon.
Yassmin TahaMohammed Kassab Institute of Orthopaedics, La Manouba, Tunisia.
Wafa HamdiDepartment of Rheumatology Kassab Institute UR17SP04 Tunis El Manar University Faculty of Medicine of Tunis, Mannouba, Tunisia.
Samah IsmailSuez Canal University, Ismailia, Egypt.
Hanane Lassoued FerjaniDepartment of Rheumatology Kassab Institute UR17SP04 Tunis El Manar University Faculty of Medicine of Tunis, Mannouba, Tunisia.
Chafia Makhloufi DahouDepartment of Rheumatology, Med Lamine Debaghine University Hospital, BabEl oued, BD Said Touati, Algiers, Algeria.
Yasmine MakhloufMohammed Kassab Institute of Orthopaedics, Mannouba, Tunisia.
Samy SlimaniPrivate practice Office, Batna, Algeria.
Christiaan ScottUniversity of Ottawa, Ontario, Canada.
Djohra HadefFaculty of Medicine, Batna 2 University, Batna, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo develop evidence-based recommendations for diagnosis and treatment of children and adolescents with systemic juvenile idiopathic arthritis (sJIA), taking into consideration the socioeconomic status and availability of medications in African countries.

methodsA steering group composed of five PAFLAR members formulated questions in PICO format (Patient/Population, Intervention, Comparison, Outcome), conducted a systematic literature review, and identified experts in pediatric rheumatology throughout Africa. The Delphi method was used to reach consensus among the experts on the recommendations for diagnosis and treatment of sJIA patients.

resultsThe online Delphi questionnaire was sent to the 22 experts selected by the steering committee, who were asked to vote for each statement and to provide their suggestions for modifications or rewording. A 100% response rate was obtained. A minimum agreement of 70% among the voting panel was required. A total of 15 recommendations were formulated, 4 regarding diagnosis and 11 regarding treatment. The percentage of agreement with the recommendations ranged from 72.7% to 95%.

conclusionWe present the first African recommendations for diagnosis and management of sJIA. The feedback about the application of these recommendations in pediatric rheumatology centers will serve as the basis for future revisions in the light of African-specific experiences and insights.

Indexed as

Antirheumatic AgentsArthritis, JuvenileRheumatologyAdolescentAfricaChildConsensusDelphi TechniqueEvidence-Based MedicineHumansPractice Guidelines as TopicAntirheumatic AgentsJIAPAFLARRecommendationssJIA

Identifiers

PMID42875797
PMCPMC13670612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.