Evidence map›Paper›PMID 42875777›Full record

ReviewThyroid research2026

Impact of BMI on perioperative outcomes following total thyroidectomy: a systematic review and meta-analysis.

Osamah Al-Adilee, Emmanuella Habib, Dimitrios Prassas, Jasmin Mirheli, Wolfram Trudo Knoefel, Sascha Vaghiri, Levent Dizdar

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Review in Thyroid research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Osamah Al-AdileeDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Emmanuella HabibDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Dimitrios PrassasDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Jasmin MirheliMedical Research School Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Wolfram Trudo KnoefelDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Sascha Vaghiri *Department of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
Levent Dizdar *Department of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany. Levent.Dizdar@med.uni-duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe influence of body mass index (BMI) on perioperative outcomes following total thyroidectomy (TT) remains controversial. We performed a systematic review and meta-analysis to evaluate the association between BMI and perioperative complications after TT.

methodsTwelve observational studies including 22,145 patients undergoing elective TT were analyzed. BMI was categorized per WHO criteria. Primary outcomes were recurrent laryngeal nerve (RLN) palsy and hypoparathyroidism. Secondary outcomes included operative time, length of stay (LOS), postoperative bleeding, and surgical site infection (SSI). Random-effects models were used.

resultsBMI was not associated with RLN palsy. Lower BMI was associated with higher rates of postoperative and transient hypoparathyroidism, while permanent hypoparathyroidism did not differ. Higher BMI was associated with longer operative time and increased postoperative bleeding. LOS and SSI were comparable between groups.

conclusionsTotal thyroidectomy appears to be safe in patients with elevated BMI, as no significant association was observed between BMI and the predefined primary outcomes of recurrent laryngeal nerve palsy or permanent hypoparathyroidism. Interestingly, patients with lower BMI experienced higher rates of postoperative and transient hypoparathyroidism. Higher BMI was associated with longer operative time and may be associated with an increased risk of postoperative bleeding. Therefore, particular attention should be paid to meticulous intraoperative hemostasis in patients with elevated BMI.

Indexed as

BMIObesityThyroidectomy

Identifiers

PMID42875777
PMCPMC13663210

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