Semi-Artificial Photosynthesis Enables Light-Driven Biomanufacturing in Non-Photosynthetic Bacteria.

Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang

Abstract read

In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie Zheng *State Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.

Anqi Tong *State Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.

Wenxin Li *State Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.

Meng QiaoResearch Center of Pharmaceutical and Synthetic Biology/Department of Food Nutrition and Safety, College of Engineering, China Pharmaceutical University, Nanjing, China.

Yang GuState Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.ORCID https://orcid.org/0000-0001-6360-3982

Muhammad SohailState Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.ORCID https://orcid.org/0000-0003-0772-7723

Shan HeFaculty of Science, Technology and Engineering, Charles Darwin University, Northern Territory, Australia.ORCID https://orcid.org/0000-0002-2698-0786

Sheng YangKey Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID https://orcid.org/0000-0003-3742-9989

Xing ZhangState Key Laboratory of Microbial Technology, School of Food Science and Pharmaceutical Engineering, Jiangsu Key Laboratory for Peptide Biosynthesis, Nanjing Normal University, Nanjing, China.ORCID https://orcid.org/0000-0002-2699-3448

Funding

Jiangsu Province Natural Science Funds for Distinguished Young Scholar BK20240032National Natural Science Foundation of China U25D9012Special Science and Technology Innovation Program for Carbon Peak and Carbon Neutralization of Jiangsu Province BT2025014

6 · The paper itself

Abstract

Semiconductor biohybrid systems integrate microbial biosynthesis with semiconductor light harvesting to sustainably power energy-intensive chemical production. Although such systems have been widely explored in photosynthetic bacteria, extending them to non-photosynthetic biomanufacturing chassis such as Bacillus subtilis (B. subtilis) remains substantially more challenging, owing to peptidoglycan-induced nanoparticle aggregation and mass-transfer limitations, cytotoxicity, and inefficient interfacial electron transfer from loose adsorption between inorganic semiconductors and cells. Here, we propose a non-invasive enhancement strategy that leverages the endogenous hydrogen sulfide (H

Indexed as

bacillus subtiliscadmium sulfidelight‐driven biomanufacturingsemi‐artificial photosynthesissemiconductor biohybrid

Identifiers

PMID42875735

DOI10.1002/advs.78265

PMCPMC13669208

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.