Can grip strength capture what chair standing does? methodological considerations on functional measures and successful aging in three international cohorts.

Zebo Kudratova, Azamat Karabaev, Vazira Raxmanova, Arofat Sadikova, Shahlo Axmadjonova, Farzan Vira Bagheri

Abstract readLetter

In one paragraph

Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Zebo KudratovaDepartment of Clinical Laboratory Diagnostics, Samarkand State Medical University, Samarkand, Uzbekistan.

Azamat KarabaevDepartment of Pathological Physiology, Physiology and Hygiene, Zarmed University, Samarkand, Uzbekistan.

Vazira RaxmanovaBukhara State Pedagogical Institute, Bukhara, Uzbekistan.

Arofat SadikovaTashkent State Medical University, Tashkent, Uzbekistan.

Shahlo AxmadjonovaDepartment of Communal and Occupational Hygiene, Fergana Medical Institute of Public Health, Fergana, Uzbekistan.

Farzan Vira BagheriSchool of Medicine, Guilan University of Medical Sciences, Rasht, Iran. vafaeebagherifarzaneh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population aging has accelerated globally, making successful aging a key public health priority. Zhuang and Gao address the prospective association between cumulative average grip strength and successful aging using three international cohorts. While their multi-cohort design offers valuable cross-population insights, several methodological choices warrant consideration. Grip strength may not fully capture functional determinants of successful aging. Self-reported chronic disease introduces misclassification bias varying across socioeconomic groups. The two-stage temporal design does not fully address selection bias and cross-cohort comparability from heterogeneous exposure windows. Additionally, the cohort-relative cognitive threshold undermines cross-population comparability. These considerations highlight the need for methodological reflection and suggest directions for strengthening future multi-cohort studies.

Indexed as

AgingHand StrengthHealthy AgingStanding PositionAgedCohort StudiesHumansCognitive assessmentGrip strengthMulti-cohort studySelection biasSelf-reported outcomesSuccessful aging

Identifiers

PMID42875631

DOI10.1007/s40520-026-03523-z

PMCPMC13668958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.