Evidence map›Paper›PMID 42875501›Full record

ArticleNature2026

Sexual dimorphism in epidermal stem cell dynamics.

Dan Engelman, Joel Hochstetter, Anaïs Bauduin, Sagar Patil, Marta Valenti, Yura Song, Qiuyu Lian, Annagiada Toniolo, Mohammad Ghiasloo, Nordin Bansaccal and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Dan Engelman *Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID http://orcid.org/0000-0003-2915-1200
Joel Hochstetter *Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK.
Anaïs Bauduin *Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Sagar PatilEli and Edythe Broad CIRM Center for Regenerative Medicine, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0008-3568-4461
Marta ValentiCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Yura SongLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID http://orcid.org/0000-0002-1173-9172
Qiuyu LianDepartment of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK.
Annagiada TonioloVIB Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0001-6332-6225
Mohammad GhiaslooVIB Center for Inflammation Research, Ghent, Belgium.
Nordin BansaccalLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID http://orcid.org/0000-0002-7240-2100
Anne-Lise DelaunoisLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Mélanie LiagreLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Michele De LucaCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0000-0002-0850-8445
Esther HosteVIB Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0002-3181-431X
Laura De RosaCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Yulia ShwartzEli and Edythe Broad CIRM Center for Regenerative Medicine, Los Angeles, CA, USA.
Benjamin D SimonsDepartment of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK. bds10@cam.ac.uk.ORCID http://orcid.org/0000-0002-3875-7071
Cédric BlanpainLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium. cedric.blanpain@ulb.be.ORCID http://orcid.org/0000-0002-4028-4322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermis is a stratified epithelium comprising proliferative basal cells and differentiated suprabasal cells that are continuously renewed throughout life. Conflicting theories have been proposed regarding the heterogeneity of the basal cell layer, with some studies proposing that all proliferative cells have self-renewal potential during homeostasis

Identifiers

PMID42875501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.