ArticleNature2026
Divergent genomic evolution in astrocytomas and oligodendrogliomas.
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Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
70 authors.
Tamrin Chowdhury *Department of Neurosurgery, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-6747-6316
C Mircea S Tesileanu *Department of Neurosurgery, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-3541-9242
Emre Kocakavuk *Department of Neurosurgery, Yale University, New Haven, CT, USA.
Kevin C JohnsonDepartment of Neurosurgery, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-0016-5158
Joo Ho LeeDepartment of Neurosurgery, Yale University, New Haven, CT, USA.
Zeynep Erson-OmayDepartment of Neurosurgery, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-1839-5912
Chaewon HeoDepartment of Neurosurgery, Yale University, New Haven, CT, USA.
Kenneth AldapeNational Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-5119-7550
Samirkumar B AminDepartment of Neurosurgery, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-3207-9505
Kevin J AndersonThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.ORCID http://orcid.org/0000-0002-2362-273X
David M AshleyPreston Robert Tisch Brain Tumor Center at Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0002-4754-5900
Floris P BarthelTranslational Genomics Research Institute, Phoenix, AZ, USA.ORCID http://orcid.org/0000-0002-7425-4180
Jill S Barnholtz-SloanNational Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0001-6190-9304
Daniel J BratDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Andrew R BrodbeltWalton Centre NHS Foundation Trust, Liverpool, UK.
Ana Valeria CastroHermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford Health, Detroit, MI, USA.ORCID http://orcid.org/0000-0003-1625-0015
Elizabeth B ClausDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Jennifer M ConnellyDepartment of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Joseph F CostelloDepartment of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-3189-584X
Indrani DattaHermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford Health, Detroit, MI, USA.
Carol ElliottSt Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Gaetano FinocchiaroDepartment of Neurology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID http://orcid.org/0000-0003-3583-4040
Pim J FrenchDepartment of Neurology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-0668-9529
Hui K GanCancer Therapies and Biology Laboratory, Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia.
Luciano GarofanoDepartment of Public Health Sciences, Division of Biostatistics and Bioinformatics, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID http://orcid.org/0000-0001-8582-0865
Padmaja L GhospurkarThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Anna GolebiewskaNORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg.ORCID http://orcid.org/0000-0002-4160-2521
Pranav S GundlaDepartment of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), National Center for Tumor Diseases (NCT) West, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.ORCID http://orcid.org/0000-0002-3726-1445
Beth HermesSt Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Chibo HongDepartment of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA.
Youri HoogstrateDepartment of Neurology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2166-0676
Craig HorbinskiDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-8340-9992
Jason T HuseUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0003-4514-0640
Antonio IavaroneSylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID http://orcid.org/0000-0002-0683-4634
Cihat KaradagDepartment of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), National Center for Tumor Diseases (NCT) West, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Mustafa KhasrawPreston Robert Tisch Brain Tumor Center at Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0003-3249-9849
Mathilde C M KouwenhovenDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-5252-4365
Peter S LaVioletteDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Kay LiDepartment of Pathology, Prince of Wales Hospital, Hong Kong, China.
Allison LowmanDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Katy McCortneyDepartment of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7085-830X
Hyo-Eun MoonDepartment of Neurosurgery, Cancer Research Institute, Hypoxia/Ischemia Disease Institute, Seoul National University, Seoul, Republic of Korea.
Nader SanaiIvy Brain Tumor Center at the Barrow Neurological Institute, Phoenix, AZ, USA.
MacLean P NasrallahGlioblastoma Translational Center of Excellence, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-4861-0898
H K NgDepartment of Pathology, Prince of Wales Hospital, Hong Kong, China.
D Ryan OrmondDepartment of Neurosurgery, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Bethany KwanDepartment of Emergency Medicine, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Marta PadovanDepartment of Neurology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Sun Ha PaekDepartment of Neurosurgery, Cancer Research Institute, Hypoxia/Ischemia Disease Institute, Seoul National University, Seoul, Republic of Korea.
Laila M PoissonHermelin Brain Tumor Center, Department of Neurosurgery, Henry Ford Health, Detroit, MI, USA.
Sushant PuriOregon Health & Science University, Portland, OR, USA.
Erica ShenDepartment of Neurosurgery, Yale University, New Haven, CT, USA.
Shwetal MehtaIvy Brain Tumor Center at the Barrow Neurological Institute, Phoenix, AZ, USA.
Andrew E SloanNeurological Institute, Premier Health and Wright State University School of Medicine, Dayton, OH, USA.ORCID http://orcid.org/0000-0001-9607-5063
Wies R VallentgoedDepartment of Neurology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Erwin G Van MeirUniversity of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Rachael VaubelDivision of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA.
Taylor E WadeThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Annemiek M E WalenkampDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Colin WattsDepartment of Cancer Genome Sciences, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0003-3531-8791
Tobias WeissDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-5533-9429
Michael WellerDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1748-174X
Pieter WesselingVUmc, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Kerryn WestcottCancer Therapies and Biology Laboratory, Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia.
Bart A WestermanDepartment of Neurosurgery, VUmc, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-9898-9616
Gordon Y YeThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.ORCID http://orcid.org/0000-0003-2105-6954
W K Alfred YungDepartment of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0002-1669-0793
GLASS Consortium
Frederick S VarnThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. frederick.varn@jax.org.ORCID http://orcid.org/0000-0001-6307-016X
Roel G W VerhaakDepartment of Neurosurgery, Yale University, New Haven, CT, USA. roel.verhaak@yale.edu.ORCID http://orcid.org/0000-0003-2773-0436
Funding
No grant is acknowledged in the PubMed record.
Abstract
Astrocytomas and oligodendrogliomas are isocitrate dehydrogenase (IDH)-mutant gliomas that most commonly arise in adults under the age of 50 and exhibit variable responses to treatment
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PMID
42875489What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.