Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension.

Ying Xia, Yan Sui, Guo-Chao Zhang, Si-Yi Yang, Wen-Fu Lu, Ping-An Wu

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Review in Brazilian journal of otorhinolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Ying XiaDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China; School of Medicine, Shenzhen University, Shenzhen, Guangdong, P.R. China.

Yan SuiDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China; School of Medicine, Shenzhen University, Shenzhen, Guangdong, P.R. China.

Guo-Chao ZhangDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China; School of Medicine, Shenzhen University, Shenzhen, Guangdong, P.R. China.

Si-Yi YangDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China.

Wen-Fu LuDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China; School of Medicine, Shenzhen University, Shenzhen, Guangdong, P.R. China.

Ping-An WuDivision of Head and Neck Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, P.R. China. Electronic address: wupa@hku-szh.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study reports our experience with multidisciplinary surgical management of lacrimal gland malignant tumors with intracranial extension using the orbitocranial approach.

methodsWe reviewed treatment strategies and surgical approaches for lacrimal gland malignant tumors with intracranial extension and present 2 illustrative patients who underwent orbitocranial resection at our institution in 2015. Clinical records, radiographic images, histologic sections, and archived pathology specimens were reviewed.

resultsBoth patients underwent orbitocranial tumor resection, followed by postoperative chemoradiotherapy. Orbital reconstruction was performed using a temporalis fascia flap and split calvarial bone grafts, with split-thickness skin grafting to line the orbital cavity. The follow-up periods were 69- and 66-months, respectively. Both patients remained alive without evidence of disease recurrence during follow-up.

conclusionsThe orbitocranial approach, combined with postoperative chemoradiotherapy, may provide satisfactory local and regional control in selected patients with lacrimal gland malignant tumors with intracranial extension. Long-term surveillance remains important because patients may remain at risk for disease recurrence or distant metastasis.

Indexed as

Intracranial extensionLacrimal gland carcinomaOrbital exenterationOrbitocranial approachSkull base surgery

Identifiers

PMID42874303

DOI10.1016/j.bjorl.2026.101921

PMCPMC13683437

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