Evidence map›Paper›PMID 42873866›Full record

ArticleScience advances2026

Radical-induced autoxidation dominates squalene oxidative aging under environmental conditions.

Xinke Wang, Jillian P Downey, Giulia Gobbi, William D Fahy, Wanqi Wu, Linna Xie, Xingwang Hou, Hui Peng, Jonathan P D Abbatt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinke WangShanghai Key Laboratory of Air Quality and Environmental Health (LAP3), Department of Environmental Science & Engineering, Fudan University, Shanghai 200438, China.ORCID 0000-0003-4848-0616
Jillian P DowneyDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0009-0005-9462-6964
Giulia GobbiDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0009-0003-2412-8674
William D FahyDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0002-2822-4474
Wanqi WuShanghai Key Laboratory of Air Quality and Environmental Health (LAP3), Department of Environmental Science & Engineering, Fudan University, Shanghai 200438, China.
Linna XieDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.
Xingwang HouDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.
Hui PengDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0002-2000-1647
Jonathan P D AbbattDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0002-3372-334X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ozone has been viewed as the principal oxidant of skin oils and other unsaturated surface films, but their fate under realistic indoor conditions remains poorly constrained. Here, we use squalene (SQ), a major component of skin lipids, to investigate the dominant oxidation pathways in occupied indoor environments and laboratory flow reactors. With exposure to indoor air, SQ decay and reactive oxygen species (ROS) formation accelerated over time, consistent with autoxidation. Laboratory experiments with ozone alone drove first-order SQ loss and humidity-dependent emissions of volatile organic compounds (VOCs). In contrast, exposure to both ozone and

Identifiers

PMID42873866
PMCPMC13665947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.