Evidence map›Paper›PMID 42873859›Full record

ArticleScience advances2026

Maternal vaccination with capsular polysaccharide bioconjugates protects against murine

Paeton L Wantuch, Jessica Tung, Lloyd S Robinson, Isra Darwech, Cory J Knoot, Christian M Harding, Drew J Schwartz, David A Rosen

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paeton L WantuchDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-6993-6320
Jessica TungDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-6388-4868
Lloyd S RobinsonOmniose, St. Louis, MO 63110, USA.
Isra DarwechOmniose, St. Louis, MO 63110, USA.ORCID 0000-0002-5042-3568
Cory J KnootOmniose, St. Louis, MO 63110, USA.
Christian M HardingOmniose, St. Louis, MO 63110, USA.ORCID 0000-0002-2158-3546
Drew J SchwartzDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-1568-7733
David A RosenDepartment of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-1081-772X

Funding

Protective immunity elicited by distinct polysaccharide antigens of classical and hypervirulent KlebsiellaR01AI175038 · NIAID · WASHINGTON UNIVERSITY · PI ROSEN, DAVID A. · 2023 to 2025
$3.5M
A capsule-based bioconjugate vaccine to prevent Klebsiella pneumoniae infectionsR44AI167078 · NIAID · VAXNEWMO, LLC · PI Christian Harding · 2025 to 2026
$2.0M
Antibiotic disruption of the gut microbiome and immune response in neonatal late-onset sepsisK08AI159384 · NIAID · WASHINGTON UNIVERSITY · PI SCHWARTZ, DREW JOEL · 2021 to 2025
$785k
Maternal vaccination to prevent Klebsiella pneumoniae gut colonization and neonatal sepsisR01AI195492 · NIAID · WASHINGTON UNIVERSITY · PI David A. Rosen, DREW Joel SCHWARTZ · 2026 to 2026
$727k
NIAID NIH HHS K08 AI159384NIAID NIH HHS R01 AI175038NIAID NIH HHS R01 AI195492NIAID NIH HHS R44 AI167078
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial CapsulesBacterial VaccinesKlebsiella InfectionsKlebsiella pneumoniaeNeonatal SepsisPolysaccharides, BacterialAnimalsAnimals, NewbornAntibodies, BacterialDisease Models, AnimalFemaleImmunity, Maternally-AcquiredMicePregnancyVaccinationVaccines, ConjugateAntibodies, BacterialBacterial VaccinesPolysaccharides, BacterialVaccines, Conjugate

Identifiers

PMID42873859
PMCPMC13665941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.