Evidence map›Paper›PMID 42873814›Full record

ArticleMicrobiologyOpen2026

Molecular Insights Into Hypervirulent Klebsiella pneumoniae: Identification and Correlation of Virulence Determinant.

Fathy M Elkady, Nosiba S Basher, Mohammed S Abdulrahman, Amr H Hashem, Rafik Abdellatif Metwally, Ahmed Abdel Tawab, Ebrahim Saied, Nasir A Ibrahim, Mohammed Aufy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fathy M ElkadyMicrobiology and Immunology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-0915-2556
Nosiba S BasherDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Mohammed S AbdulrahmanMicrobiology and Immunology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-0102-3637
Amr H HashemDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-0024-3606
Rafik Abdellatif MetwallyDepartment of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.ORCID https://orcid.org/0009-0002-9612-0850
Ahmed Abdel TawabDepartment of Microbiology and Immunology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Ebrahim SaiedDepartment of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt.ORCID https://orcid.org/0000-0002-5622-7912
Nasir A IbrahimDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Mohammed AufyDepartment of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-6693-4530

Funding

No external funding was received for the work and authorship
6 · The paper itself

Abstract

Klebsiella pneumoniae is an increasingly important opportunistic pathogen worldwide, particularly due to the emergence and spread of hypervirulent K. pneumoniae (hvKP), a clinically significant pathotype first identified in Taiwan. This study aimed to molecularly identify hvKP isolates screened for coexisting virulence determinants and evaluate the association between specific virulence genes and hypervirulence. Clinical specimens were collected from hospitalized patients, and K. pneumoniae isolates were identified phenotypically using microscopic culture characteristics and biochemical assays and genotypically confirmed by PCR targeting the khe gene. Hypermucoviscosity regulators

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeVirulence FactorsBacterial ProteinsGenotypeHumansPolymerase Chain ReactionTaiwanVirulenceBacterial ProteinsVirulence FactorsbiomarkershypervirulentK. pneumoniaemucoid regulatorsiderophoresstring test

Identifiers

PMID42873814
PMCPMC13667796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.