ArticlePloS one2026
Factors influencing tuberculosis preventive treatment implementation in India: A hybrid inductive-abductive thematic analysis using implementation framework.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndia has committed to achieving 'Eliminate Tuberculosis (TB)' by 2025. The Government of India issued guidelines regarding the crucial strategy of Tuberculosis Preventive Treatment in July 2021.
objectivesTo identify factors influencing tuberculosis preventive treatment program implementation and acceptance of tuberculosis preventive treatment.
methodsWe conducted the study in the Pune district from April to August 2024. It was a qualitative study using Focus Group Discussions (FGD) with Medical Officers (MO) and adult contacts of the index case, and In-depth Interviews (IDI) with senior health officers. We conducted eight FGDs with MOs and six with adult contacts, and conducted in-depth interviews with senior health officers. Data were transcribed, translated, and analyzed using MAXQDA.
resultsEighty-six health/medical officers and 43 adult contacts participated in FGD and IDI. Some health officers have received training in tuberculosis but not in preventive treatment. Knowledge about tuberculosis preventive treatment and duration was minimal. Medical officers minimally briefed contacts. Stigma mainly from contacts perspectives, migration from health personnels perspectives and lack of awareness from both the groups emerged as important factors influencing screening and treatment of adult contacts. Very few underwent blood/ X-ray/ sputum testing, and fewer received treatment for varied durations. Medical officers knew only the isoniazid regimen, and interferon-gamma release assay testing was either unknown or unavailable. There is a shortage of trained human resources. The supply of diagnostic kits and medicines was disrupted. Health personnel and contacts recommended non-pharmacological measures such as mask use, cleanliness, and good nutrition. All officers perceived that elimination may linger until 2030. Training, counselling, community awareness, and multi-sectoral collaboration were strategies suggested by health officers.
conclusionsHealth personnel capacity building, strengthening infrastructure and logistics, multiple strategies to mitigate stigma, and multi-sectoral collaboration are needed to satisfactory implementation of TB preventive treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.