Evidence map›Paper›PMID 42873300›Full record

ReviewMarine biotechnology (New York, N.Y.)2026

Marine-Derived Extracellular Vesicles: Bioinspired Nanobiomaterials for Skin Regeneration and Dermatological Applications.

Afsona Khatun, Rahul Samanta, Ananda Mohan Dutta, Imtiaz Kabir, Sajal Kumar Jha, Thirumal M

Abstract readReview
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In one paragraph

Review in Marine biotechnology (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Afsona KhatunDepartment of Pharmacognosy, Faculty of Medicine and Health Sciences, SRM College of Pharmacy, SRM Institute of Science and Technology, 603203, Kattankulathur, Chengalpattu, Tamil Nadu, India.
Rahul SamantaBengal College of Pharmaceutical Technology, 731123, Dubrajpur, Birbhum, West Bengal, India.
Ananda Mohan DuttaBengal College of Pharmaceutical Technology, 731123, Dubrajpur, Birbhum, West Bengal, India.
Imtiaz KabirBengal College of Pharmaceutical Technology, 731123, Dubrajpur, Birbhum, West Bengal, India.
Sajal Kumar JhaBengal College of Pharmaceutical Technology, 731123, Dubrajpur, Birbhum, West Bengal, India.
Thirumal MDepartment of Pharmacognosy, Faculty of Medicine and Health Sciences, SRM College of Pharmacy, SRM Institute of Science and Technology, 603203, Kattankulathur, Chengalpattu, Tamil Nadu, India. thirumam@srmist.edu.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) represent a significant advancement in the study of biological nanocarriers, facilitating intercellular communication by transferring proteins, lipids, and nucleic acids. Although there has been considerable research into mammalian-derived EVs, the exploration of marine-derived EVs is relatively limited, despite their significant potential as bioinspired biomaterials. The marine environment, characterized by extreme physicochemical conditions and significant biodiversity, produces EVs that exhibit distinctive molecular cargo, improved structural stability, and adaptive functional properties. This review presents an in-depth look of marine-derived EVs from a biomaterial's perspective, emphasizing their biological origins, physicochemical properties, methods for isolation and purification, and advanced characterization techniques. Moreover, the mechanistic functions of marine EVs in skin regeneration are clarified, highlighting preclinical evidence supporting the application of these treatments for wound healing, inflammatory skin disorders, photoaging, pigmentation abnormalities, and skin cancer therapy. Despite the potential for favourable results, obstacles concerning large-scale production, standardization, and the translation of regulatory frameworks persist. This review highlights marine-derived EVs as a novel category of functional biomaterials, demonstrating considerable potential for advancing skin regenerative and dermatological applications in future research.

Indexed as

Aquatic OrganismsBiocompatible MaterialsExtracellular VesiclesRegenerationSkinAnimalsHumansSkin DiseasesSkin Physiological PhenomenaWound HealingBiocompatible MaterialsBiomaterialsDermatological applicationsMarine-derived EVsSkin cancer therapySkin regeneration

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.