Evidence map›Paper›PMID 42873237›Full record

ArticleMedizinische Klinik, Intensivmedizin und Notfallmedizin2026

[Acute heart failure-management during the first 120 min : Approach for early stabilization and decongestion].

M Buerke, H Lemm, A Amerini, P Boettger

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Article in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M BuerkeMedizinische Klinik II, Kardiologie, Angiologie, Internistische Intensivmedizin, St.-Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland. mbuerke@gmail.com.ORCID https://orcid.org/0009-0009-5477-9957
H LemmMedizinische Klinik II, Kardiologie, Angiologie, Internistische Intensivmedizin, St.-Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland.ORCID https://orcid.org/0000-0003-3131-2827
A AmeriniZentrale Notaufnahme, St.-Marien-Krankenhaus Siegen, Siegen, Deutschland.
P BoettgerMedizinische Klinik I, Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum der Justus-Liebig-Universität, Gießen, Deutschland.ORCID https://orcid.org/0009-0004-0534-132X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute heart failure (AHF) is among the most common causes of emergency department, intermediate care, and intensive care unit admission and remains associated with substantial early mortality despite advances in contemporary therapy. The first 120 min of management are particularly critical, as this period determines not only respiratory and hemodynamic stabilization, but also trigger identification, decongestion strategy, and the foundation for subsequent prognostic improvement. This CME article provides a practical, phenotype-based approach to the early management of AHF. The proposed strategy is centered on the rapid classification of patients according to congestion ("wet" vs. "dry") and perfusion ("warm" vs. "cold") status. Stabilization and diagnostic work-up must occur simultaneously. Early assessment should focus on identifying acute coronary syndrome, clinically relevant arrhythmias, hypertensive crisis, pulmonary embolism, structural heart disease, and infectious triggers. In addition to clinical examination, electrocardiography, blood gas analysis, and biomarkers, point-of-care ultrasound with lung ultrasound and focused echocardiography play a pivotal role in the first-line evaluation. From a therapeutic perspective, early noninvasive ventilation in cardiogenic pulmonary edema, prompt vasodilation in hypertensive presentations, and effective decongestion with intravenous loop diuretics constitute the core interventions. In cases of insufficient response, escalation strategies such as sequential nephron blockade or selective use of vasoactive agents should be considered. Structured reassessment at short intervals is essential to detect persistent congestion, evolving hypoperfusion, inadequate therapeutic response, or overlooked differential diagnoses. The article emphasizes that successful acute management must already establish the transition toward guideline-directed long-term therapy during the first hours of hospitalization, including early initiation of evidence-based heart failure medication once hemodynamic stabilization has been achieved.

Indexed as

Cardiac arrhythmiasCardiovascular diseasesHemodynamicsHypoxiaPulmonary edema

Identifiers

PMID42873237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.