Evidence map›Paper›PMID 42872801›Full record

ArticleAnnals of medicine2026

Association between quality of life and pregnancy outcomes among infertility patients undergoing assisted reproduction technologies: a prospective cohort study.

Pengfei Qu, Yu Zhang, Yiting Li, Kangxin Wang, Qiyue Hu, Lu Gao, Xiaojie Fu, Sirui Liang, Fuyang Zhao, Siyi Ren and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Pengfei QuAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.ORCID 0000-0002-2644-5812
Yu ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yiting LiDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Kangxin WangDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Qiyue HuDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Lu GaoAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Xiaojie FuAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Sirui LiangAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Fuyang ZhaoSchool of Nursing, Shaanxi University of Chinese Medicine, Xian yang, Shaanxi, China.
Siyi RenSchool of Nursing, Shaanxi University of Chinese Medicine, Xian yang, Shaanxi, China.
Sifan HeSchool of Nursing, Shaanxi University of Chinese Medicine, Xian yang, Shaanxi, China.
Yuan LiuThe Center of Medical Genetics, Northwest Women's and Children's Hospital, Xi'an, Shaanxi Province, China.
Yuanyuan ManAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Doudou ZhaoAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Xu CaoAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Juanzi ShiAssisted Reproduction Center, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility and its treatment impose significant psychosocial burdens that impair quality of life (QoL). Its impact on pregnancy outcomes after embryo transfer (ET) in assisted reproduction technologies (ART) remains underexplored.

objectiveThis study prospectively examined the association between QoL-measured by the FertiQoL instrument-and cumulative live birth rates (CLBRs) in women undergoing ART.

methodsIn this prospective cohort study, 1,233 women initiating IVF/ICSI completed the FertiQoL questionnaire pretreatment. Latent profile analysis (LPA) identified distinct QoL subgroups based on domain scores. Multivariable regression models, adjusted for confounders, assessed associations between QoL profiles/scores and pregnancy outcomes, with CLBRs as the primary endpoint. Smoothed curve fitting and threshold analyses explored nonlinear relationships.

resultsLPA delineated three FertiQoL subgroups: Low (

conclusionQoL was significantly associated with CLBRs following ET. A threshold effect was evident: improvements in QoL below a score of 74.306 were associated with higher live birth rates. These findings underscore the importance of integrating QoL assessment and intervention into infertility care.

Indexed as

InfertilityPregnancy OutcomeQuality of LifeReproductive Techniques, AssistedAbortion, SpontaneousAdultEmbryo TransferFemaleFertilization in VitroHumansLive BirthPregnancyPregnancy RateProspective StudiesSurveys and Questionnairescumulative live birth ratesembryo transferFertility quality of life toolLatent profile analysispregnancy outcome

Identifiers

PMID42872801
PMCPMC13670262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.